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本文引用的文献

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Opioid Prescribing After Childbirth and Risk for Serious Opioid-Related Events: A Cohort Study.产后阿片类药物处方与严重阿片类药物相关事件风险:一项队列研究
Ann Intern Med. 2020 Sep 1;173(5):412-414. doi: 10.7326/M19-3805. Epub 2020 Jun 9.
2
The Implausibility of Neonatal Opioid Toxicity from Breastfeeding.母乳喂养导致新生儿阿片类药物中毒的不可信性。
Clin Pharmacol Ther. 2020 Nov;108(5):964-970. doi: 10.1002/cpt.1882. Epub 2020 Jun 25.
3
Neonatal Abstinence Syndrome Incidence and Health Care Costs in the United States, 2016.2016 年美国新生儿戒断综合征的发病率和医疗保健费用。
JAMA Pediatr. 2020 Feb 1;174(2):200-202. doi: 10.1001/jamapediatrics.2019.4791.
4
Rates of New Persistent Opioid Use After Vaginal or Cesarean Birth Among US Women.美国女性阴道分娩或剖宫产术后新发持续性阿片类药物使用的发生率。
JAMA Netw Open. 2019 Jul 3;2(7):e197863. doi: 10.1001/jamanetworkopen.2019.7863.
5
Pregnancy outcome following opioid exposure: A cohort study.孕期暴露于阿片类药物后的结局:一项队列研究。
PLoS One. 2019 Jul 1;14(7):e0219061. doi: 10.1371/journal.pone.0219061. eCollection 2019.
6
Accuracy of five self-report screening instruments for substance use in pregnancy.五种用于妊娠期间物质使用的自我报告筛查工具的准确性。
Addiction. 2019 Sep;114(9):1683-1693. doi: 10.1111/add.14651. Epub 2019 Jun 19.
7
EEG Findings in Infants With Neonatal Abstinence Syndrome Presenting With Clinical Seizures.患有临床癫痫发作的新生儿戒断综合征婴儿的脑电图表现
Front Pediatr. 2019 Mar 29;7:111. doi: 10.3389/fped.2019.00111. eCollection 2019.
8
Accuracy of Three Screening Tools for Prenatal Substance Use.三种产前物质使用筛查工具的准确性。
Obstet Gynecol. 2019 May;133(5):952-961. doi: 10.1097/AOG.0000000000003230.
9
Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006-2015.先天性腹裂趋势与阿片类药物处方率的生态关联 - 美国,2006-2015 年。
MMWR Morb Mortal Wkly Rep. 2019 Jan 18;68(2):31-36. doi: 10.15585/mmwr.mm6802a2.
10
The Burden of Opioid-Related Mortality in the United States.美国阿片类药物相关死亡率负担。
JAMA Netw Open. 2018 Jun 1;1(2):e180217. doi: 10.1001/jamanetworkopen.2018.0217.

孕期阿片类药物的使用:一场新出现的健康危机。

Opioid use in pregnancy: An emerging health crisis.

作者信息

Zipursky Jonathan, Juurlink David N

机构信息

Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

出版信息

Obstet Med. 2021 Dec;14(4):211-219. doi: 10.1177/1753495X20971163. Epub 2020 Dec 6.

DOI:10.1177/1753495X20971163
PMID:34880933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8646213/
Abstract

Opioid use in pregnancy has increased in parallel to the opioid crisis observed in the general population. Rising rates of peripartum opioid use pose a significant public health concern for both mothers and their children. Pregnancy also represents a unique opportunity for healthcare providers to screen women for opioid use disorder and engage them in appropriate care. In the present review, we describe patterns of opioid use in pregnancy and how this relates to maternal and neonatal health outcomes. We also examine screening for and treatment of opioid use disorder in pregnancy, neonatal outcomes following maternal opioid use, and breastfeeding recommendations for women taking opioids postpartum.

摘要

孕期阿片类药物的使用与普通人群中观察到的阿片类药物危机同步增加。围产期阿片类药物使用比例的上升对母亲及其子女都构成了重大的公共卫生问题。怀孕也为医疗保健提供者提供了一个独特的机会,来筛查女性是否患有阿片类药物使用障碍,并让她们接受适当的护理。在本综述中,我们描述了孕期阿片类药物的使用模式及其与孕产妇和新生儿健康结局的关系。我们还研究了孕期阿片类药物使用障碍的筛查和治疗、母亲使用阿片类药物后的新生儿结局,以及对产后服用阿片类药物的女性的母乳喂养建议。