Ranaei-Zamani Niccole, Kaler Mandeep K, Khan Rehan
The Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, UK.
Obstet Med. 2021 Dec;14(4):253-256. doi: 10.1177/1753495X20970791. Epub 2020 Dec 28.
Proteus syndrome is a rare, multi-system, genetic syndrome characterised by atypical and excessive growth of skeletal tissue. Clinical presentations include abnormal musculoskeletal growth and cutaneous lesions. Due to its rarity, there have been a limited number of published case reports of Proteus syndrome. This is the first case report on the management of Proteus syndrome in pregnancy. We present the case of a pregnant woman with Proteus syndrome in her first pregnancy in a large teaching hospital and discuss the considerations and challenges faced in her antenatal, intrapartum and postnatal care.
变形综合征是一种罕见的多系统遗传性综合征，其特征为骨骼组织的异常过度生长。临床表现包括骨骼肌肉生长异常和皮肤病变。由于其罕见性，已发表的变形综合征病例报告数量有限。这是首例关于妊娠期变形综合征管理的病例报告。我们介绍了一名在大型教学医院首次怀孕的患有变形综合征的孕妇病例，并讨论了她在产前、产时和产后护理中面临的考虑因素和挑战。
