Department of Ultrasound Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, China.
Department of Ultrasound, Wuhan Red Cross Hospital, Wuhan, Hubei Province 430015, China.
J Healthc Eng. 2021 Nov 29;2021:6835963. doi: 10.1155/2021/6835963. eCollection 2021.
Breast cancer is a common gynecological disease, and its incidence and mortality are higher than those of other common malignant tumors. Breast ultrasound technology is a new surgical method, which has the advantages of reducing postoperative complications, improving the quality of life of patients, and improving the prognosis of patients. Breast microcalcification is a new method for the treatment of tumors. Its mechanism is that the proliferation of breast cancer cell walls increases the inflammatory factors in the cancer tissues and enhances the formation of tumors and peripheral vascular thrombosis. Breast microcalcification in the treatment of breast cancer patients will have a more significant impact compared to ordinary antibiotics alone. For this reason, the microcalcification performance of breast ultrasound is worthy of study, and related research on prognosis is also indispensable. The purpose of this study is to improve the understanding of the ultrasound manifestations of breast cancer microcalcification and the prognosis of breast cancer. This article mainly applied statistical analysis as well as experimental and survey methods to conduct breast ultrasound examination on 100 patients and analyzed the ultrasound manifestations of breast cancer MCs from three aspects: location, shape, and distribution. The experimental results show that there is no correlation between the location and distribution of breast cancer MCs and the diameter of the cancer foci, but there is a certain correlation between the morphology (non-gravel-like calcification) and the diameter of the cancer foci (>5 cm). Among them, HER-2 overexpression accounted for 11.9% in the grit-like MCs group and 51% in the non-grit-like MCs group.
乳腺癌是一种常见的妇科疾病，其发病率和死亡率均高于其他常见恶性肿瘤。乳腺超声技术是一种新的手术方法，具有减少术后并发症、提高患者生活质量、改善患者预后等优点。乳腺微钙化是一种治疗肿瘤的新方法。其机制是乳腺癌细胞壁的增殖增加了癌症组织中的炎症因子，增强了肿瘤和周围血管血栓的形成。乳腺微钙化在治疗乳腺癌患者方面比单独使用普通抗生素更有显著效果。因此，乳腺超声的微钙化表现值得研究，相关预后研究也不可或缺。本研究旨在提高对乳腺癌微钙化的超声表现和乳腺癌预后的认识。本文主要应用统计分析以及实验和调查方法对 100 名患者进行了乳腺超声检查，并从位置、形态和分布三个方面分析了乳腺癌 MC 的超声表现。实验结果表明，乳腺癌 MC 的位置和分布与癌灶直径之间无相关性，但形态（非砂粒样钙化）与癌灶直径（>5cm）之间存在一定相关性。其中，HER-2 过表达在砂粒样 MCs 组中占 11.9%，在非砂粒样 MCs 组中占 51%。
