PET/RM Unit, Department of Experimental and Clinical Medicine, and Neuroscience Research Center, Magna Graecia University of Catanzaro, Catanzaro, Italy -
Unit of Nuclear Medicine, Mater Domini University Hospital, Catanzaro, Italy -
Q J Nucl Med Mol Imaging. 2021 Dec;65(4):327-332. doi: 10.23736/S1824-4785.21.03418-X. Epub 2021 Dec 9.
Nuclear medicine therapeutic procedures have considerably expanded over the last few years, and their number is expected to grow exponentially in the future. Internal dosimetry has significantly developed as well, but has not yet been uniformly accepted as a valuable tool for prediction of therapeutic efficacy and toxicity. In this paper, we briefly summarize some of the arguments about the implementation of internal dosimetry in clinical practice. In addition, we provide a few examples of radionuclide anticancer therapies for which internal dosimetry demonstrated a significant impact on treatment optimization and patient outcome.
核医学治疗程序在过去几年中得到了极大的扩展，预计未来其数量将呈指数级增长。内剂量测定也有了显著的发展，但尚未被普遍接受为预测治疗效果和毒性的有价值的工具。本文简要总结了一些关于在临床实践中实施内剂量测定的争论。此外，我们还提供了一些放射性核素抗癌治疗的例子，其中内剂量测定对治疗优化和患者预后产生了重大影响。
