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评估临床病例研究中的患者特异性微波乳腺成像。

Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies.

机构信息

Electronic and Electrical Engineering, Trinity College Dublin, D02 PN40 Dublin, Ireland.

Electrical and Electronic Engineering, National University of Ireland Galway, H91 TK33 Galway, Ireland.

出版信息

Sensors (Basel). 2021 Dec 1;21(23):8048. doi: 10.3390/s21238048.

Abstract

Microwave breast imaging has seen increasing use in clinical investigations in the past decade with over eight systems having being trialled with patients. The majority of systems use radar-based algorithms to reconstruct the image shown to the clinician which requires an estimate of the dielectric properties of the breast to synthetically focus signals to reconstruct the image. Both simulated and experimental studies have shown that, even in simplified scenarios, misestimation of the dielectric properties can impair both the image quality and tumour detection. Many methods have been proposed to address the issue of the estimation of dielectric properties, but few have been tested with patient images. In this work, a leading approach for dielectric properties estimation based on the computation of many candidate images for microwave breast imaging is analysed with patient images for the first time. Using five clinical case studies of both healthy breasts and breasts with abnormalities, the advantages and disadvantages of computational patient-specific microwave breast image reconstruction are highlighted.

摘要

在过去十年中,微波乳房成像在临床研究中得到了越来越多的应用,已有超过 8 个系统在患者身上进行了试验。大多数系统使用基于雷达的算法来重建显示给临床医生的图像,这需要估计乳房的介电特性,以便对信号进行合成聚焦以重建图像。模拟和实验研究都表明,即使在简化的情况下,介电特性的错误估计也会影响图像质量和肿瘤检测。已经提出了许多方法来解决介电特性估计的问题,但很少有方法用患者图像进行测试。在这项工作中,首次使用患者图像分析了一种基于计算许多候选微波乳房成像图像的领先介电特性估计方法。使用五个临床案例研究,包括健康乳房和异常乳房,突出了计算特定于患者的微波乳房图像重建的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c9/8659731/8466eabfd122/sensors-21-08048-g001.jpg

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