Méndez Lucía, Castro Pedro, Ferreira Jorge, Caneiras Cátia
Pneumology Department, Centro Hospitalar de Entre Douro e Vouga, 4520-221 Santa Maria da Feira, Portugal.
EnviHealthMicro Lab, Microbiology Research Laboratory on Environmental Health, Institute of Environmental Health (ISAMB), Faculty of Medicine, Universidade de Lisboa, 1649-028 Lisboa, Portugal.
J Clin Med. 2021 Nov 28;10(23):5593. doi: 10.3390/jcm10235593.
Pneumonia is one of the main causes of hospitalization and mortality. It's the fourth leading cause of death worldwide. Healthcare-associated infections are the most frequent complication of healthcare and affect hundreds of millions of patients around the world, although the actual number of patients affected is unknown due to the difficulty of reliable data. The main goal of this manuscript is to describe the epidemiological characteristics of patients admitted with pneumonia and the impact of healthcare-associated pneumonia (HCAP) in those patients. It is a quantitative descriptive study with retrospective analysis of the clinical processes of 2436 individuals for 1 year (2018) with the diagnosis of pneumonia. The individuals with ≤5 years old represented 10.4% ( = 253) and ≥65 were 72.6% ( = 1769). 369 cases resulted in death, which gives a sample lethality rate of 15.2%. The severity and mortality index were not sensitive to the death event. We found 30.2% ( = 735) individuals with HCAP and 0.41% ( = 59) with ventilator-associated pneumonia (VAP). In only 59 individuals (2.4%) the agent causing pneumonia was isolated. The high fatality rate obtained shows that pneumonia is a major cause of death in vulnerable populations. Moreover, HCAP is one of the main causes of hospital admissions from pneumonia and death and the most pneumonias are treated empirically. Knowledge of the epidemiology characterization of pneumonia, especially associated with healthcare, is essential to increase the skills of health professionals for the prevention and efficient treatment of pneumonia.
肺炎是住院和死亡的主要原因之一。它是全球第四大死因。医疗保健相关感染是医疗保健中最常见的并发症,影响着全球数亿患者,不过由于难以获得可靠数据,实际受影响患者数量未知。本手稿的主要目的是描述肺炎住院患者的流行病学特征以及医疗保健相关肺炎(HCAP)对这些患者的影响。这是一项定量描述性研究,对2018年诊断为肺炎的2436名个体的临床过程进行回顾性分析。5岁及以下个体占10.4%(n = 253),65岁及以上个体占72.6%(n = 1769)。369例导致死亡,样本致死率为15.2%。严重程度和死亡率指数对死亡事件不敏感。我们发现30.2%(n = 735)的个体患有HCAP,0.41%(n = 59)的个体患有呼吸机相关性肺炎(VAP)。仅在59名个体(2.4%)中分离出了引起肺炎的病原体。所获得的高死亡率表明肺炎是弱势群体死亡的主要原因之一。此外,HCAP是肺炎导致住院和死亡的主要原因之一,并且大多数肺炎是经验性治疗。了解肺炎的流行病学特征,尤其是与医疗保健相关的特征,对于提高卫生专业人员预防和有效治疗肺炎的技能至关重要。