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Focal Point of Fanconi Anemia Signaling.
Int J Mol Sci. 2021 Nov 30;22(23):12976. doi: 10.3390/ijms222312976.
2
Deficiency of the Fanconi anemia core complex protein FAAP100 results in severe Fanconi anemia.
J Clin Invest. 2025 Apr 17;135(11). doi: 10.1172/JCI185126. eCollection 2025 Jun 2.
3
ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway.
J Cell Biol. 2025 Jul 7;224(7). doi: 10.1083/jcb.202407141. Epub 2025 Jun 20.
4
FANCD2 and DNA Damage.
Int J Mol Sci. 2017 Aug 19;18(8):1804. doi: 10.3390/ijms18081804.
5
The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.
J Biol Chem. 2014 Sep 12;289(37):25774-82. doi: 10.1074/jbc.M114.552570. Epub 2014 Jul 28.
6
Structural basis of Fanconi anemia pathway activation by FANCM.
EMBO J. 2025 May 30. doi: 10.1038/s44318-025-00468-3.
7
Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors.
Front Med (Lausanne). 2024 Oct 3;11:1462810. doi: 10.3389/fmed.2024.1462810. eCollection 2024.
8
miR-29a-3p and TGF-β Axis in Fanconi anemia: mechanisms driving metabolic dysfunction and genome stability.
Cell Mol Life Sci. 2025 Jun 25;82(1):255. doi: 10.1007/s00018-025-05775-w.
10
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.
Nat Commun. 2018 Jun 11;9(1):2280. doi: 10.1038/s41467-018-04649-z.

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2
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma.
NPJ Precis Oncol. 2025 Feb 5;9(1):37. doi: 10.1038/s41698-025-00819-7.
3
Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors.
Front Med (Lausanne). 2024 Oct 3;11:1462810. doi: 10.3389/fmed.2024.1462810. eCollection 2024.
4
Research progress on the fanconi anemia signaling pathway in non-obstructive azoospermia.
Front Endocrinol (Lausanne). 2024 May 23;15:1393111. doi: 10.3389/fendo.2024.1393111. eCollection 2024.
5
Epidemiology and distribution of 207 rare diseases in China: A systematic literature review.
Intractable Rare Dis Res. 2024 May 31;13(2):73-88. doi: 10.5582/irdr.2024.01001.
7
FANCI serve as a prognostic biomarker correlated with immune infiltrates in skin cutaneous melanoma.
Front Immunol. 2023 Nov 22;14:1295831. doi: 10.3389/fimmu.2023.1295831. eCollection 2023.

本文引用的文献

1
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation.
Cell Death Dis. 2021 Aug 9;12(8):780. doi: 10.1038/s41419-021-04034-7.
2
Promyelocytic Leukemia Proteins Regulate Fanconi Anemia Gene Expression.
Int J Mol Sci. 2021 Jul 21;22(15):7782. doi: 10.3390/ijms22157782.
3
PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair.
Cancers (Basel). 2021 Jul 18;13(14):3604. doi: 10.3390/cancers13143604.
4
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Dev Cell. 2021 Aug 9;56(15):2207-2222.e7. doi: 10.1016/j.devcel.2021.06.010. Epub 2021 Jul 12.
5
Cyclin-Dependent Kinase-Mediated Phosphorylation of FANCD2 Promotes Mitotic Fidelity.
Mol Cell Biol. 2021 Jul 23;41(8):e0023421. doi: 10.1128/MCB.00234-21.
6
Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum.
Cancers (Basel). 2021 Mar 22;13(6):1442. doi: 10.3390/cancers13061442.
7
Beyond DNA repair and chromosome instability-Fanconi anaemia as a cellular senescence-associated syndrome.
Cell Death Differ. 2021 Apr;28(4):1159-1173. doi: 10.1038/s41418-021-00764-5. Epub 2021 Mar 15.
8
Cancer Statistics, 2021.
CA Cancer J Clin. 2021 Jan;71(1):7-33. doi: 10.3322/caac.21654. Epub 2021 Jan 12.
9
TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response.
Aging (Albany NY). 2020 Oct 24;12(20):20268-20284. doi: 10.18632/aging.103782.

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