2016-2018 年布尔萨乌鲁达大学医学院人群中 感染的血清流行率。
Serological Prevalence of in Faculty of Medicine of Bursa Uludağ University During 2016-2018.
机构信息
Bursa Uludağ Üniversitesi Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Bursa, Türkiye
出版信息
Turkiye Parazitol Derg. 2021 Dec 2;45(4):257-261. doi: 10.4274/tpd.galenos.2021.52824.
OBJECTIVE
This study aimed to retrospectively investigate IgG and IgM distribution and IgG avidity in serum samples with suspected toxoplasmosis in the medical microbiology serology laboratory of Faculty of Medicine Hospital at Bursa Uludağ University over a 24-month period (January 2016 to December 2018).
METHODS
An enzyme-linked fluorescent assay using the VIDAS automated analyzer (BioMérieux, France) was used to determine IgM antibodies, IgG antibodies, and IgG avidity.
RESULTS
The IgM antibody positivity was found to be 1.7% (101/6104), whereas the IgG antibody positivity was 37.9% (1.149/3024). The seropositivity of IgG was 31.5% in women belonging to the childbearing age group. In this group, IgG high and low avidity rates were 70.1% (134/191) and 15.2% (29/191), respectively.
CONCLUSION
Screening and diagnosis of toxoplasma serology in women of childbearing age is important. The results of this study may be useful for designing optimal control and preventive measures against infection.
目的
本研究旨在回顾性调查布尔萨大学医学院附属医院医学微生物学血清学实验室在 24 个月期间（2016 年 1 月至 2018 年 12 月）疑似弓形虫病患者血清样本中 IgG 和 IgM 的分布及 IgG 亲合力。
方法
采用 VIDAS 自动分析仪（法国生物梅里埃公司）酶联荧光分析法检测 IgM 抗体、IgG 抗体和 IgG 亲合力。
结果
IgM 抗体阳性率为 1.7%（101/6104），而 IgG 抗体阳性率为 37.9%（1.149/3024）。处于生育年龄组的女性 IgG 血清阳性率为 31.5%。在该组中，IgG 高亲和率和低亲和率分别为 70.1%（134/191）和 15.2%（29/191）。
结论
对生育年龄妇女进行弓形虫血清学筛查和诊断很重要。本研究结果可为制定针对感染的最佳控制和预防措施提供参考。
Zotero 插件