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氰基丙烯酸酯注射治疗 Boerhaave 综合征术后漏:一例报告。

Cyanoacrylate injection treatment for postoperative leakage of Boerhaave's syndrome: A case report.

机构信息

Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University School of Medicine, Seoul, Korea.

出版信息

Medicine (Baltimore). 2021 Dec 10;100(49):e28075. doi: 10.1097/MD.0000000000028075.

Abstract

RATIONALE

Surgical treatment remains the most effective option for treating Boerhaave's syndrome. However, in cases of postoperative anastomotic leakage of Boerhaave's syndrome, endoscopic interventions such as over-the-scope clip, stenting, or cyanoacrylate injection have emerged over reoperation.

PATIENT CONCERNS

We report the case of a 50-year-old male patient who presented with vomiting and abdominal pain after alcohol consumption. Laparoscopic surgery was performed for primary closure of a laceration at the lower esophagus, and for the closure of a Boerhaave's syndrome, which was detected by abdominal computed tomography. However, postoperative anastomotic leakage was confirmed through esophagography after the operation. In our case, endoscopic treatment with an over-the-scope clip and stenting were not effective for the repair of the anastomotic leakage, but cyanoacrylate injection successfully healed the anastomotic leakage.

DIAGNOSES

Boerhaave's syndrome was initially detected by abdominal computed tomography, but postoperative anastomotic leakage after the operation was confirmed with esophagography.

INTERVENTIONS

A total of 2.0 cc of N-butyl-2-cyanoacrylate and lipiodol mixture (at 1:1) was injected into the leakage tract through the perforation entrance.

OUTCOMES

Complete healing of the anastomotic leakage was confirmed with a follow-up esophagoscopy.

LESSONS

N-butyl-2-cyanocrylate injection treatment can be used as a rescue option for postoperative leakage when over-the-scope clips and stenting fail for this indication.

摘要

背景

手术治疗仍然是治疗 Boerhaave 综合征的最有效选择。然而,对于 Boerhaave 综合征术后吻合口漏的病例,内镜介入治疗,如内镜下夹闭、支架置入或氰基丙烯酸酯注射,已取代再次手术。

病例报告

我们报告了一例 50 岁男性患者,因饮酒后呕吐和腹痛就诊。因食管下段裂伤行腹腔镜手术一期缝合,因腹部 CT 发现 Boerhaave 综合征而行剖腹手术。但术后吻合口漏通过食管造影确诊。在我们的病例中,内镜下夹闭和支架置入治疗对吻合口漏的修复无效,但氰基丙烯酸酯注射成功治愈了吻合口漏。

诊断

最初通过腹部 CT 检测到 Boerhaave 综合征,但术后吻合口漏通过食管造影确诊。

干预措施

通过穿孔入口向漏道内注射总共 2.0 毫升 N-丁基-2-氰基丙烯酸酯和碘油混合物(1:1)。

结果

通过随访食管镜检查确认吻合口漏完全愈合。

结论

对于这种情况下内镜下夹闭和支架置入治疗失败的术后漏,N-丁基-2-氰基丙烯酸酯注射治疗可以作为一种挽救选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34c6/8663892/e794ff766f8b/medi-100-e28075-g001.jpg

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