Department of General Surgery, Affiliated People's Hospital, Jiangsu University, Zhenjiang, Jiangsu Province, China.
Department of Ophthalmology, Affiliated People's Hospital, Jiangsu University, Zhenjiang, Jiangsu Province, China.
Medicine (Baltimore). 2021 Dec 10;100(49):e28137. doi: 10.1097/MD.0000000000028137.
Agenesis of the dorsal pancreas (ADP) is a rare congenital anomaly of the pancreas. ADP is associated with some other medical problems such as diabetes mellitus, abdominal pain/bloating, pancreatitis, pancreatic neuroendocrine tumor and so on. In this study, we present a case of ADP with chronic suppurative pancreatitis, summarize the clinical characteristics of the reported cases in China and review the correlative literature.
A 51-year-old Chinese man, with a history of impaired fasting glucose, presented with jaundice, pruritus and dark urine. Laboratory analysis showed abnormal liver function and elevated carbohydrate antigen 19-9.
Contrast-enhanced computed tomography demonstrated a mass located at the head of pancreas and complete absence of the body and tail of pancreas. Endoscopic retrograde cholangiopancreatography demonstrated an eccentric malignant stricture about 1.6cm of distal common bile duct.
The patient underwent pancreaticoduodenectomy because of the suspicion of pancreatic tumor. The postoperative pathological result was chronic suppurative pancreatitis, with moderate hyperplasia in focal ductal epithelium.
A long-term follow-up shows that the patient is asymptomatic with well-controlled diabetes mellitus and pancreatic exocrine insufficiency.
ADP is a quite rare congenital malformation of the pancreas with poorly-understood pathogenesis. The diagnosis of ADP depends on the imaging examination. The therapeutic strategy varies from person to person due to the different accompanying conditions.
背侧胰发育不全（ADP）是一种罕见的胰腺先天性畸形。ADP 与其他一些医学问题有关，如糖尿病、腹痛/腹胀、胰腺炎、胰腺神经内分泌肿瘤等。在本研究中，我们报告了一例 ADP 合并慢性化脓性胰腺炎的病例，总结了中国报道病例的临床特征，并复习了相关文献。
一名 51 岁的中国男性，有空腹血糖受损史，表现为黄疸、瘙痒和深色尿。实验室分析显示肝功能异常和碳水化合物抗原 19-9 升高。
增强 CT 显示胰头部有一肿块，胰体和胰尾完全缺失。内镜逆行胰胆管造影显示胆总管下段 1.6cm 偏心恶性狭窄。
因怀疑胰腺肿瘤，患者行胰十二指肠切除术。术后病理结果为慢性化脓性胰腺炎，局部导管上皮中度增生。
长期随访显示患者无症状，糖尿病和胰腺外分泌功能不全得到良好控制。
ADP 是一种相当罕见的胰腺先天性畸形，发病机制尚不清楚。ADP 的诊断依赖于影像学检查。由于不同的伴随情况，治疗策略因人而异。
