Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ontario, Canada.
School of Epidemiology & Public Health, University of Ottawa, Ontario, Canada.
Br J Health Psychol. 2022 Sep;27(3):822-843. doi: 10.1111/bjhp.12575. Epub 2021 Dec 10.
Increasing deceased organ donation registration may increase the number of available organs for transplant to help save lives. This study aimed to identify which behaviour change techniques (BCTs; or 'active ingredients') are reported within randomized trials of interventions promoting deceased organ donation registration and of those, which are associated with a larger intervention effect.
We conducted a secondary analysis of 45 trials included in a Cochrane systematic review of deceased organ donation registration interventions. Two researchers used the BCT Taxonomy v1 to independently code intervention content in all trial groups. Outcome data were pooled and we used meta-regression to explore associations between individual and combinations of recurring BCTs and effect on registration intention and/or registration behaviour.
A total of 27 different BCTs (mean = 3.7, range = 1-9) were identified in intervention groups across the 45 trials. The five most common BCTs were: 'Information about health consequences' (71%); 'Instruction on how to perform the behaviour' (47%); 'Salience of consequences' (40%); 'Adding objects to the environment' (28%); and 'Credible source' (27%). Comparator groups in 20/45 trials also included identifiable BCTs (n = 12, mean = 3.1, range = 1-7). Meta-regression revealed that a combination of the three most common BCTs was associated with a larger intervention effect size for registration behaviour (k = 8, β = .19, p = .02).
Trials of deceased organ donation registration interventions focus predominantly on providing information, instruction, and a means to register. While potentially effective, a much wider set of possible BCTs could be leveraged to address known barriers to registration.
增加已故器官捐献登记人数可能会增加可用于移植的器官数量，从而帮助挽救生命。本研究旨在确定在促进已故器官捐献登记的干预措施随机试验中报告了哪些行为改变技术（BCT；或“有效成分”），以及这些 BCT 与更大的干预效果相关。
我们对一项关于已故器官捐献登记干预措施的 Cochrane 系统评价中包含的 45 项试验进行了二次分析。两位研究人员使用 BCT 分类学 v1 独立对所有试验组的干预内容进行编码。汇总了结局数据，并使用元回归来探索单个和重复出现的 BCT 组合与对登记意向和/或登记行为的影响之间的关联。
在 45 项试验的干预组中，共确定了 27 种不同的 BCT（平均=3.7，范围=1-9）。最常见的 5 种 BCT 为：“关于健康后果的信息”（71%）；“关于如何实施行为的指导”（47%）；“后果的凸显性”（40%）；“向环境中添加物体”（28%）；“可信来源”（27%）。在 20/45 项试验中，对照组也包含可识别的 BCT（n=12，平均=3.1，范围=1-7）。元回归显示，最常见的 3 种 BCT 的组合与更大的登记行为干预效果相关（k=8，β=0.19，p=0.02）。
已故器官捐献登记干预措施的试验主要集中在提供信息、指导和登记手段上。虽然这些方法可能有效，但可以利用更广泛的 BCT 集合来解决已知的登记障碍。
