Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:3309-3312. doi: 10.1109/EMBC46164.2021.9629671.
Convolutional neural networks have become popular in medical image segmentation, and one of their most notable achievements is their ability to learn discriminative features using large labeled datasets. Two-dimensional (2D) networks are accustomed to extracting multiscale features with deep convolutional neural network extractors, i.e., ResNet-101. However, 2D networks are inefficient in extracting spatial features from volumetric images. Although most of the 2D segmentation networks can be extended to three-dimensional (3D) networks, extended 3D methods are resource and time intensive. In this paper, we propose an efficient and accurate network for fully automatic 3D segmentation. We designed a 3D multiple-contextual extractor (MCE) to simulate multiscale feature extraction and feature fusion to capture rich global contextual dependencies from different feature levels. We also designed a light 3D ResU-Net for efficient volumetric image segmentation. The proposed multiple-contextual extractor and light 3D ResU-Net constituted a complete segmentation network. By feeding the multiple-contextual features to the light 3D ResU-Net, we realized 3D medical image segmentation with high efficiency and accuracy. To validate the 3D segmentation performance of our proposed method, we evaluated the proposed network in the context of semantic segmentation on a private spleen dataset and public liver dataset. The spleen dataset contains 50 patients' CT scans, and the liver dataset contains 131 patients' CT scans.
卷积神经网络在医学图像分割中已经得到了广泛的应用,其最显著的成就之一是能够使用大型标记数据集学习有区别的特征。二维(2D)网络习惯于使用深度卷积神经网络提取器(即 ResNet-101)提取多尺度特征。然而,2D 网络在从体积图像中提取空间特征方面效率不高。尽管大多数 2D 分割网络都可以扩展到三维(3D)网络,但扩展的 3D 方法需要大量的资源和时间。在本文中,我们提出了一种用于全自动 3D 分割的高效、准确的网络。我们设计了一个 3D 多上下文提取器(MCE),以模拟多尺度特征提取和特征融合,从不同的特征层次捕获丰富的全局上下文依赖关系。我们还设计了一个轻量级的 3D ResU-Net,用于高效的体积图像分割。所提出的多上下文提取器和轻量级 3D ResU-Net 构成了一个完整的分割网络。通过将多上下文特征输入到轻量级 3D ResU-Net 中,我们实现了高效、准确的 3D 医学图像分割。为了验证我们提出的方法在 3D 分割性能方面的有效性,我们在一个私有脾脏数据集和一个公共肝脏数据集的语义分割背景下评估了所提出的网络。脾脏数据集包含 50 名患者的 CT 扫描,肝脏数据集包含 131 名患者的 CT 扫描。