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铁缺乏性贫血治疗期间伴心脏受累的可逆性脑血管收缩综合征:病例报告。

Reversible cerebral vasoconstriction syndrome with cardiac involvement during treatment for iron deficiency anemia: caser report.

机构信息

Department of Neurology, National Hospital Organization Matsumoto Medical Center, 2-20-30 Muraimachi-minami, Matsumoto, 399-8701, Japan.

出版信息

BMC Neurol. 2021 Dec 10;21(1):479. doi: 10.1186/s12883-021-02509-w.

Abstract

BACKGROUND

The diagnosis and therapy of reversible cerebral vasoconstriction syndrome (RCVS) tends to focus on neurological symptoms, but less attention has been paid the occurrence of extracerebral lesion such as the myocardium.

CASE PRESENTATION

A 40-year-old woman taking iron supplements for iron deficiency anemia due to menorrhagia had suffered from a thunderclap headache and seizure. Brain magnetic resonance imaging revealed high-intensity lesions bilaterally in the cerebellar and cerebral hemispheres. Her symptoms once subsided with steroids and anticonvulsant therapy; however, she experienced a severe headache again while bathing and was transferred to our hospital. Based on the clinical course and imaging data, she was diagnosed as having RCVS triggered by a rapid improvement of anemia. At the same time, she had cardiac involvement revealed by electro and echocardiographs despite without chest symptoms. After the administration of a calcium channel blocker and nitrite, her cerebral and cardiac involvements were rapidly improved.

CONCLUSIONS

The case presented RCVS with transient myocardial damage. With RCVS, we should always pay attention to the complication of extracerebral lesions.

摘要

背景

可逆性脑血管收缩综合征(RCVS)的诊断和治疗往往侧重于神经系统症状,但对心肌等脑外病变的发生关注较少。

病例介绍

一名 40 岁女性因月经过多导致缺铁性贫血正在服用铁补充剂,突发霹雳头痛和癫痫发作。脑部磁共振成像显示双侧小脑和大脑半球呈高强度病变。她的症状曾一度缓解,接受了类固醇和抗惊厥治疗;然而,她在洗澡时再次出现剧烈头痛,被转至我院。根据临床过程和影像学数据,她被诊断为由贫血迅速改善引发的 RCVS。同时,尽管没有胸部症状,但心电图和超声心动图显示她有心脏受累。钙通道阻滞剂和亚硝酸盐给药后,她的脑部和心脏受累迅速改善。

结论

本例呈现短暂性心肌损伤的 RCVS。对于 RCVS,我们应始终注意脑外病变的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7faf/8662846/909e10aeeb5a/12883_2021_2509_Fig1_HTML.jpg

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