Department of Orthopaedic, Trauma and Plastic Surgery, University Hospital Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Center for Research On Musculoskeletal Systems (ZESBO), Faculty of Medicine, University of Leipzig, Leipzig, Germany.
Sci Rep. 2021 Dec 10;11(1):23816. doi: 10.1038/s41598-021-03336-2.
The goal of this study is to compare the construct stability of long segmental dorsal stabilization in unstable midthoracic osteoporotic fractures with complete pedicle screw cement augmentation (ComPSCA) versus restricted pedicle screw cement augmentation (ResPSCA) of the most cranial and caudal pedicle screws under cyclic loading. Twelve fresh frozen human cadaveric specimens (Th4-Th10) from individuals aged 65 years and older were tested in a biomechanical cadaver study. All specimens received a DEXA scan and computer tomography (CT) scan prior to testing. All specimens were matched into pairs. These pairs were randomized into the ComPSCA group and ResPSCA group. An unstable Th7 fracture was simulated. Periodic bending in flexion direction with a torque of 2.5 Nm and 25,000 cycles was applied. Markers were applied to the vertebral bodies to measure segmental movement. After testing, a CT scan of all specimens was performed. The mean age of the specimens was 87.8 years (range 74-101). The mean T-score was - 3.6 (range - 1.2 to - 5.3). Implant failure was visible in three specimens, two of the ComPSCA group and one of the ResPSCA group, affecting only one pedicle screw in each case. Slightly higher segmental movement could be evaluated in these three specimens. No further statistically significant differences were observed between the study groups. The construct stability under cyclic loading in flexion direction of long segmental posterior stabilization of an unstable osteoporotic midthoracic fracture using ResPSCA seems to be comparable to ComPSCA.
本研究的目的是比较在循环加载下,使用完整的椎弓根螺钉水泥增强(ComPSCA)与限制椎弓根螺钉水泥增强(ResPSCA)对最颅侧和尾侧椎弓根螺钉进行不稳定的骨质疏松性中胸段骨折的长节段后向稳定的结构稳定性。在生物力学尸体研究中,对 12 个来自年龄在 65 岁及以上个体的新鲜冷冻人体尸体标本(Th4-Th10)进行了测试。所有标本在测试前均接受 DEXA 扫描和计算机断层扫描(CT)扫描。所有标本均配对。这些配对随机分为 ComPSCA 组和 ResPSCA 组。模拟不稳定的 Th7 骨折。周期性地在弯曲方向施加 2.5 Nm 的扭矩和 25000 次循环。在椎体上标记以测量节段运动。测试后,对所有标本进行 CT 扫描。标本的平均年龄为 87.8 岁(范围 74-101)。平均 T 评分-3.6(范围-1.2 至-5.3)。可见 3 个标本出现植入物失败,其中 2 个来自 ComPSCA 组,1 个来自 ResPSCA 组,每个病例仅影响一个椎弓根螺钉。在这三个标本中,可以评估出稍高的节段运动。在研究组之间未观察到进一步具有统计学意义的差异。使用 ResPSCA 对不稳定骨质疏松性中胸段骨折进行长节段后向稳定的循环加载下的结构稳定性,似乎与 ComPSCA 相当。