Hayashi M, Kobayashi H, Kawano H, Handa Y, Noguchi Y, Shirasaki N, Hirose S
No To Shinkei. 1986 Jul;38(7):685-91.
The authors studied brain blood flow with single photon emission computed tomography (SPECT) in two patients with plateau waves. The intracranial pressure and blood pressure were also monitored continuously in these patients. They included one patient with brain-tumor (rt. sphenoid ridge meningioma) and another with hydrocephalus after subarachnoid hemorrhage due to rupture of lt. internal carotid aneurysm. The intracranial pressure was monitored through an indwelling ventricular catheter attached to a pressure transducer. The blood pressure was recorded through an intraarterial catheter placed in the dorsalis pedis artery. Brain blood flow was studied with Headtome SET-011 (manufactured by Shimazu Co., Ltd.). For this flow measurement study, an intravenous injection of Xenon-133 of about 30 mCi was given via an antecubital vein. The position of the slice for the SPECT was selected so as to obtain information not only from the cerebral hemisphere but also from the brain stem: a cross section 25 degrees over the orbito-meatal line, passing through the inferior aspect of the frontal horn, the basal ganglia, the lower recessus of the third ventricle and the brain stem. The results indicated that, in the cerebral hemisphere, plateau waves were accompanied by a decrease in blood flow, whereas, in the brain stem, the blood flow showed little change during plateau waves as compared with the interval phase between two plateau waves. These observations may explain why there is no rise in the blood pressure and why patients are often alert during plateau waves.
作者用单光子发射计算机断层扫描（SPECT）研究了2例出现高原波患者的脑血流量。同时对这些患者的颅内压和血压进行了连续监测。其中1例为脑肿瘤患者（右侧蝶骨嵴脑膜瘤），另1例为左侧颈内动脉瘤破裂导致蛛网膜下腔出血后的脑积水患者。通过连接压力传感器的留置脑室导管监测颅内压。通过置于足背动脉的动脉内导管记录血压。使用Headtome SET - 011（岛津公司制造）研究脑血流量。在这项血流测量研究中，经肘前静脉静脉注射约30 mCi的氙 - 133。选择SPECT切片的位置，以便不仅从大脑半球而且从脑干获取信息：在眶耳线以上25度的横截面，穿过额角下侧、基底神经节、第三脑室下隐窝和脑干。结果表明，在大脑半球，高原波伴随着血流减少，而在脑干，与两个高原波之间的间隔期相比，高原波期间血流变化不大。这些观察结果可能解释了为什么血压没有升高以及为什么患者在高原波期间通常保持清醒。
