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10 年单中心使用经皮腋动脉内置式主动脉球囊反搏泵治疗心力衰竭的经验。

Ten-year, single center experience of ambulatory axillary intra-aortic balloon pump support for heart failure.

机构信息

Department of Surgery, University of Chicago Medicine, Chicago, IL, USA.

Department of Surgery, University of Chicago Medicine, Chicago, IL, USA.

出版信息

J Cardiol. 2022 May;79(5):611-617. doi: 10.1016/j.jjcc.2021.11.010. Epub 2021 Dec 9.

Abstract

BACKGROUND

The axillary intra-aortic balloon pump has an advantage over the femoral intra-aortic balloon pump in terms of mobility. While axillary intra-aortic balloon pump has been widely used recently as a mode of mechanical circulatory support, the number of reported cases is limited. The purpose of this study is to summarize our experience and to evaluate the safety and efficacy of axillary intra-aortic balloon pump support.

METHODS

Between July 2009 and July 2019, 241 patients underwent axillary intra-aortic balloon pump support for heart failure. The intended therapeutic goals were bridge to heart transplantation (n=146), left ventricular assist device (n=66), and recovery (n=29). Intra-aortic balloon pumps were inserted through a graft sutured onto the axillary artery in 142 patients (58.9%) and percutaneously in 99 patients (41.1%). It was placed from the right axillary artery in 147 patients (61.0%) and left in 94 patients (39.0%). Primary outcome measures of interest included achievement of intended therapeutic goal, hemodynamic data, ambulatory data, intra-aortic balloon pump-related death, and complications.

RESULTS

Ambulation was possible in 217 patients (90.0%) during support. Hemodynamic parameters improved significantly after axillary intra-aortic balloon pump support. In total, 13 patients (5.4%) died and 10 patients (4.1%) required escalation of mechanical support. There were no deaths directly attributable to intra-aortic balloon pumps. Intra-aortic balloon pump-related stroke occurred in 6 patients (2.5%). Overall, 86.7% were successfully bridged to intended therapy (transplantation 90.4%, left ventricular assist device 90.9%, and recovery 58.6%).

CONCLUSIONS

Axillary intra-aortic balloon pumps allow most patients to ambulate during support, improve hemodynamics, and lead to the intended goals successfully.

摘要

背景

在移动性方面,腋部主动脉内球囊泵优于股部主动脉内球囊泵。尽管腋部主动脉内球囊泵最近已广泛用作机械循环支持的模式,但报告的病例数量有限。本研究的目的是总结我们的经验,并评估腋部主动脉内球囊泵支持的安全性和有效性。

方法

在 2009 年 7 月至 2019 年 7 月期间,241 例心力衰竭患者接受腋部主动脉内球囊泵支持。预期的治疗目标是桥接心脏移植(n=146)、左心室辅助装置(n=66)和恢复(n=29)。142 例患者(58.9%)通过缝合在腋动脉上的移植物插入主动脉内球囊泵,99 例患者(41.1%)经皮插入。147 例患者(61.0%)从右腋动脉放置,94 例患者(39.0%)从左腋动脉放置。主要观察指标包括实现预期治疗目标、血流动力学数据、活动数据、与主动脉内球囊泵相关的死亡和并发症。

结果

在支持期间,217 例患者(90.0%)可以活动。腋部主动脉内球囊泵支持后,血流动力学参数显著改善。总共有 13 例患者(5.4%)死亡,10 例患者(4.1%)需要升级机械支持。没有与主动脉内球囊泵直接相关的死亡。6 例患者(2.5%)发生与主动脉内球囊泵相关的卒中。总体而言,86.7%的患者成功桥接至预期治疗(移植 90.4%,左心室辅助装置 90.9%,恢复 58.6%)。

结论

腋部主动脉内球囊泵可使大多数患者在支持期间活动,改善血液动力学,并成功实现预期目标。

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