Berezhnaia N M, Iakhimovich L V, Semenova-Kobzar' R A, Liul'kin V D, Palivets A Iu
Eksp Onkol. 1986;8(4):50-4.
Interleukin-2 is studied for its effect on proliferation of cultured tumour cells in vivo and on the nature of infiltration of malignant tumours explants of human soft tissues. On the basis of spheroid formation phenomenon and a number of morphological criteria three main types of reaction differing in inhibition or stimulation of the tumour growth, time of formation and the number of spheroids formed, manifestation of lymphocytic infiltration and nature of lymphocytes location on the filter have been distinguished.
研究了白细胞介素-2对体内培养肿瘤细胞增殖以及对人软组织恶性肿瘤外植体浸润性质的影响。基于球体形成现象和一些形态学标准，区分出了三种主要反应类型，它们在肿瘤生长的抑制或刺激、球体形成时间和形成的球体数量、淋巴细胞浸润表现以及淋巴细胞在滤膜上的定位性质等方面存在差异。
