School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, 92182, USA; The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, 1124 West Carson Street, Torrance, CA, 90502, USA.
School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, 92182, USA; College of Health Solutions, Arizona State University, Phoenix, AZ, 85004, USA.
Nutr Metab Cardiovasc Dis. 2022 Feb;32(2):479-486. doi: 10.1016/j.numecd.2021.10.016. Epub 2021 Oct 29.
This study examined the effect of moderate intensity stair stepping exercise on the glycemic response, and antioxidant capacity (TAC) during an oral glucose tolerance test (OGTT).
Thirty participants (women = 12) completed 4 OGTTs during rest or stair walking bouts of 1, 3, and 10 min in a randomized order. Blood was collected at baseline and 30 min during the OGTTs and analyzed for glucose, insulin, TAC, and lactate. Glucose concentrations were decreased following the 10 min (-22.69 (-34.66 to -10.72) mg/dL, p < 0.002) and 3 min (-15.37 (-25.05 to -5.69) mg/dL, p < 0.004) bouts but not the 1 min bout (-6.18 (-19.54 to 7.18) mg/dL, p = 0.352). Insulin concentrations were decreased following the 10 min (-6.11 (-8.86 to -3.36 μIU/dL), p < 0.001) and 3 min (-2.589 (-4.54 to -0.63) μIU/dL, p < 0.012) bouts but not the 1 min bout (-0.37 (-1.87 to 1.13) μIU/dL, p = 0.616). Insulin sensitivity index values showed a significant increase in the 10-min trial (1.81 (0.03-3.58), p < 0.048), but not during the 3 min (0.65 (-0.66 to 1.96) p = 0.317) or 1 min trial (0.13 (-1.58 to 1.84) p = 0.878). There was no omnibus effect for trial in TAC (p = 0.132, η = 0.07). There was no interaction between trial and time for blood lactate (p = 0.621, η = 0.02).
This study provides evidence bouts as short as 3 min decrease postprandial blood glucose and insulin levels but longer bouts are needed to affect insulin sensitivity.
本研究旨在探讨中等强度登楼梯运动对口服葡萄糖耐量试验（OGTT）期间血糖反应和抗氧化能力（TAC）的影响。
30 名参与者（女性=12 名）按随机顺序完成了 4 次 OGTT，分别在休息或登楼梯 1、3 和 10 分钟时进行。在 OGTT 期间的基线和 30 分钟时采集血液，用于分析血糖、胰岛素、TAC 和乳酸。与 1 分钟回合（-6.18 [ -19.54 至 -5.69 ] mg/dL，p = 0.352）相比，10 分钟回合（-22.69 [ -34.66 至 -10.72 ] mg/dL，p < 0.002）和 3 分钟回合（-15.37 [ -25.05 至 -5.69 ] mg/dL，p < 0.004）显著降低了血糖浓度，但 3 分钟回合没有降低（-6.11 [ -8.86 至 -3.36 ] μIU/dL，p < 0.001）和 3 分钟回合（-2.589 [ -4.54 至 -0.63 ] μIU/dL，p < 0.012），但 1 分钟回合没有降低（-0.37 [ -1.87 至 1.13 ] μIU/dL，p = 0.616）。胰岛素敏感性指数值在 10 分钟试验中显著增加（1.81 [ 0.03-3.58 ]，p < 0.048），但在 3 分钟试验中没有增加（0.65 [ -0.66 至 1.96 ]，p = 0.317）或 1 分钟试验中没有增加（0.13 [ -1.58 至 1.84 ]，p = 0.878）。试验的整体效果在 TAC 中没有差异（p = 0.132，η = 0.07）。在血液乳酸方面，试验与时间之间没有相互作用（p = 0.621，η = 0.02）。
本研究提供的证据表明，3 分钟的短时间登楼梯运动可降低餐后血糖和胰岛素水平，但需要更长时间的运动才能影响胰岛素敏感性。
