Alexandrová M
Endocrinol Exp. 1986 Aug;20(2-3):293-300.
The binding of 3H-dexamethasone to specific cytosol binding sites of rat mammary gland during pregnancy and lactation was characterized and quantified. During the first week of pregnancy the amount of receptor gradually increased and remained at a relatively constant level throughout pregnancy. Maximum concentration of receptor was observed immediately before labor and one day after labor. During lactation the receptor concentration gradually returned to the level observed during pregnancy and then remained at about the same level until the day 21 which was followed by a rapid decrease at the end of lactation period. No significant differences in dissociation constants were noticed during pregnancy and lactation.
对妊娠和哺乳期大鼠乳腺中3H-地塞米松与特定胞质结合位点的结合进行了表征和定量。在妊娠的第一周，受体数量逐渐增加，并在整个妊娠期保持在相对恒定的水平。在分娩前和分娩后一天观察到受体的最大浓度。在哺乳期，受体浓度逐渐恢复到妊娠期观察到的水平，然后在大约相同水平维持到第21天，随后在哺乳期结束时迅速下降。在妊娠和哺乳期未观察到解离常数的显著差异。
