Department of Gynecology and Obstetrics, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.
J Obstet Gynaecol Res. 2022 Feb;48(2):360-365. doi: 10.1111/jog.15125. Epub 2021 Dec 12.
The aim of this study was to assess postoperative pregnancy outcomes in patients with different types of submucous myomas after hysteroscopic resection.
This retrospective unicentric study used data from the electronic medical records system of the hospital. All patients (n = 77) who underwent hysteroscopy for submucous myomas between November 2010 and December 2018 were included. Patients were divided into three groups according to the myoma classification (G0, G1, and G2). Medical files were reviewed and phone questionnaires were conducted to evaluate demographic characteristics, clinical features, surgical treatment, and pregnancy outcomes.
The median age of the patients was 32 (30.0, 34.0) years. The myoma diameter was 2.9 (2.0, 3.8) cm. The operation duration was 50.0 (30.0, 75.0) min. There were 15 patients in Group G0, 20 patients in Group G1, and 37 patients in Group G2. Follow-up data were available for 65 of the 77 patients. The total pregnancy rate was 58 (89.2%) of 65. The live birth rate was 41 (70.7%) of 58. There was no significant difference in pregnancy rate (G0 100% vs. G1 76.5% vs. G2 91.2%; p = 0.097) or in live birth rates among the three groups (G0 78.6% vs. G1 53.8% vs. G2 74.2%; p = 0.325).
There was no difference in pregnancy outcome among the three types of submucosal myomas. Our results support the idea that hysteroscopic myomectomy is an effective option for submucous myomas with good long-term pregnancy outcomes.
本研究旨在评估不同类型黏膜下肌瘤患者宫腔镜切除术后的妊娠结局。
本回顾性单中心研究使用了医院电子病历系统的数据。纳入 2010 年 11 月至 2018 年 12 月期间因黏膜下肌瘤接受宫腔镜手术的所有患者（n=77）。根据肌瘤分类（G0、G1 和 G2）将患者分为三组。查阅病历并进行电话问卷调查，以评估人口统计学特征、临床特征、手术治疗和妊娠结局。
患者的中位年龄为 32（30.0，34.0）岁。肌瘤直径为 2.9（2.0，3.8）cm。手术时间为 50.0（30.0，75.0）min。G0 组 15 例，G1 组 20 例，G2 组 37 例。77 例患者中有 65 例可获得随访数据。65 例患者中总妊娠率为 58（89.2%），活产率为 41（70.7%）。三组间妊娠率（G0 100% vs. G1 76.5% vs. G2 91.2%；p=0.097）或活产率（G0 78.6% vs. G1 53.8% vs. G2 74.2%；p=0.325）均无显著差异。
三种类型的黏膜下肌瘤妊娠结局无差异。我们的结果支持宫腔镜子宫肌瘤切除术是一种治疗黏膜下肌瘤的有效方法，具有良好的长期妊娠结局。
