Department of Emergency Medicine, Washington University in St. Louis School of Medicine, Emergency Care Research Core, St. Louis, Missouri, USA.
Department of Emergency Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Acad Emerg Med. 2022 May;29(5):630-648. doi: 10.1111/acem.14427. Epub 2021 Dec 26.
Computed tomography (CT) imaging is frequently obtained for recurrent abdominal pain after a prior emergency department (ED) evaluation. We evaluate the utility of repeat CT imaging following an indeterminate index CT in low-risk abdominal pain adult ED patients.
An electronic search was designed for the patient-intervention-control-outcome-timing (PICOT) question: (P) adult patients with low-risk, recurrent, and previously undifferentiated atraumatic abdominal pain presenting to the ED after an index-negative CT within 12 months; (I) repeat CT versus (C) no repeat CT; for (O) abdominal surgery or other invasive procedure, mortality, identification of potentially life-threatening diagnosis, and hospital and intensive care unit admission rates; and return ED visit (T), all within 30 days. Four reviewers independently selected evidence for inclusion and then synthesized the results around the most prevalent themes of repeat CT timing, diagnostic yield, ionizing radiation exposure, and predictors of repetitive imaging.
Although 637 articles and abstracts were identified, no direct evidence was found. Thirteen documents were synthesized as indirect evidence. None of the indirect evidence defined a low-risk subset of abdominal pain nor did investigators describe whether reimaging occurred for complaints similar to the initial ED evaluation. Included studies did not describe the index CT findings and some reported explanatory findings noted on the original CT for which repeat CTs might have been indicated. The time frame for a repeat CT ranged from hours to 1 year. The frequency of repeat CTs (2%-47%) varied across studies as did the yield of imaging to alter downstream clinical decision making (range = 5%-67%).
Due to the absence of direct evidence our scoping review is unable to provide high-quality evidence-based recommendations upon which to confidently base an imaging practice guideline. There is no evidence to support or refute performing a CT for low-risk recurrent abdominal pain.
在先前急诊科(ED)评估后,由于反复出现腹痛,经常会进行计算机断层扫描(CT)成像。我们评估了在低风险腹痛成年 ED 患者的不确定指数 CT 后重复 CT 成像的效用。
针对患者干预对照结局时间(PICOT)问题设计了电子搜索:(P)在 12 个月内接受阴性指数 CT 后,有低风险、反复且先前未分化的无创伤性腹痛的成年患者,他们再次出现腹痛并返回 ED;(I)重复 CT 与(C)不重复 CT;(O)腹部手术或其他侵入性程序、死亡率、潜在危及生命的诊断的识别,以及住院和重症监护病房入院率;(T)所有这些都在 30 天内。四名审查员独立选择纳入的证据,然后围绕重复 CT 时间、诊断收益、电离辐射暴露以及重复成像的预测因素等最常见的主题综合结果。
尽管确定了 637 篇文章和摘要,但没有发现直接证据。综合了 13 篇文献作为间接证据。没有一篇间接证据定义了腹痛的低风险亚组,也没有研究人员描述重新成像是否是针对与最初 ED 评估相似的症状。纳入的研究未描述指数 CT 结果,有些研究报告了原始 CT 上可能提示重复 CT 的解释性发现。重复 CT 的时间范围从几小时到 1 年不等。重复 CT 的频率(2%-47%)因研究而异,成像对改变下游临床决策的效果也不同(范围=5%-67%)。
由于缺乏直接证据,我们的范围综述无法提供高质量的循证建议,从而无法有信心地制定成像实践指南。没有证据支持或反驳对低风险反复腹痛进行 CT 检查。