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流式细胞术在不明原因血细胞减少和疑似骨髓增生异常综合征患者中的临床应用:欧洲白血病网国际 MDS-流式细胞术工作组的报告。

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS-Flow Cytometry Working Group.

机构信息

Department of Hematology, Amsterdam UMC, location VU University Medical Center, Cancer Center Amsterdam, Amsterdam, The Netherlands.

MLL Munich Leukemia Laboratory, Munich, Germany.

出版信息

Cytometry B Clin Cytom. 2023 Jan;104(1):77-86. doi: 10.1002/cyto.b.22044. Epub 2021 Dec 13.

Abstract

This article discusses the rationale for inclusion of flow cytometry (FCM) in the diagnostic investigation and evaluation of cytopenias of uncertain origin and suspected myelodysplastic syndromes (MDS) by the European LeukemiaNet international MDS Flow Working Group (ELN iMDS Flow WG). The WHO 2016 classification recognizes that FCM contributes to the diagnosis of MDS and may be useful for prognostication, prediction, and evaluation of response to therapy and follow-up of MDS patients.

摘要

本文讨论了流式细胞术(FCM)在诊断不明原因血细胞减少症和疑似骨髓增生异常综合征(MDS)中的纳入标准,这是由欧洲白血病网络国际 MDS 流式细胞工作组(ELN iMDS Flow WG)提出的。2016 年版 WHO 分类认为 FCM 有助于 MDS 的诊断,并且可能有助于预后、预测、评估治疗反应以及 MDS 患者的随访。

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