Department of Nephrology Peritoneal Dialysis Center, General Hospital of Ningxia Medical University, Yinchuan, China.
Ningxia Kidney Disease Clinical Research Center, Yinchuan, China.
Ther Apher Dial. 2022 Aug;26(4):822-826. doi: 10.1111/1744-9987.13777. Epub 2022 Jan 2.
The aim of this study was to investigate how peritoneal dialysis and other influencing factors affect patients' cognitive function.
The 85 subjects in the study group were regular patients in our center. The control group included 88 age and gender matched healthy individuals who were with normal renal function. The study subjects' cognitive levels and related factors were analyzed using several screening instruments: the cognitive function was measured using the Montreal Cognitive Assessment Scale and statistical analysis was conducted based on the relevant data.
The results showed that cognitive impairment was higher in peritoneal dialysis patients than in non-dialysis subjects. Age and educational background were single factors that affected cognitive function, which was more likely to be impaired at a higher age level and/or a lower educational level.
Cognitive function can be impaired by peritoneal dialysis, and age and education levels are influencing factors.
本研究旨在探讨腹膜透析和其他影响因素如何影响患者的认知功能。
研究组 85 例患者均为我院规律腹膜透析患者,对照组为同期体检中心健康体检者 88 例,肾功能正常。采用多项认知筛查量表评估患者认知水平及其相关因素,应用蒙特利尔认知评估量表(MoCA)进行认知功能评定,对相关数据进行统计学分析。
结果显示,腹膜透析患者认知障碍发生率高于非透析患者。年龄和教育程度是影响认知功能的单一因素,年龄越高、教育程度越低,认知功能障碍的发生率越高。
腹膜透析可导致认知功能障碍,年龄和受教育程度是其影响因素。