Ji Shuohan, Qin Shengxiang, Yin Chunyu, Luo Lu, Zhang Hua
Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education and Hubei Key Laboratory of Catalysis and Materials Science, South-Central University for Nationalities, Wuhan 430074, China.
College of Chemistry, Nanchang University, Nanchang 330031, China.
Org Lett. 2022 Jan 14;24(1):64-68. doi: 10.1021/acs.orglett.1c03590. Epub 2021 Dec 13.
Unreactive C-N bond activation of anilines was achieved by photoinduced aerobic borylation. A diverse range of tertiary and secondary anilines were converted to aryl boronate esters in moderate to good yields with wide functional group tolerance under simple and ambient photochemical conditions. This transformation achieved the direct and facile C-N bond activation of unreactive anilines, providing a convenient and practical route transforming widely available anilines into useful aryl boronate esters.
通过光诱导需氧硼化实现了苯胺的惰性C-N键活化。在简单的环境光化学条件下，多种叔苯胺和仲苯胺以中等至良好的产率转化为芳基硼酸酯，具有广泛的官能团耐受性。这种转化实现了惰性苯胺的直接且简便的C-N键活化，为将广泛可得的苯胺转化为有用的芳基硼酸酯提供了一条便捷实用的途径。
