Quantile estimation of semiparametric model with time-varying coefficients for panel count data.

Panel count data frequently occurs in follow-up studies, such as medical research, social sciences, reliability studies, and tumorigenicity experiences. This type data has been extensively studied by various statistical models with time-invariant regression coefficients. However, the assumption of invariant coefficients may be violated in some reality, and the temporal covariate effects would be of great interest in research studies. This motivates us to consider a more flexible time-varying coefficient model. For statistical inference of the unknown functions, the quantile regression approach based on the B-spline approximation is developed. Asymptotic results on the convergence of the estimators are provided. Some simulation studies are presented to assess the finite-sample performance of the estimators. Finally, two applications of bladder cancer data and US flight delay data are analyzed by the proposed method.