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侵袭性肺曲霉病和肺结核合并噬血细胞性淋巴组织细胞增生症——一名肝移植受者的新冠后遗症

Invasive Pulmonary Aspergillosis and Tuberculosis Complicated by Hemophagocytic Lymphohistiocytosis - Sequelae of COVID-19 in a Liver Transplant Recipient.

作者信息

Gandotra Akash, Mehtani Rohit, Premkumar Madhumita, Duseja Ajay, De Arka, Mallik Nabhajit, Durgadevi S, Das Ashim, Kalra Naveen

机构信息

Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Hematology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Clin Exp Hepatol. 2022 May-Jun;12(3):1007-1011. doi: 10.1016/j.jceh.2021.12.002. Epub 2021 Dec 8.

Abstract

Liver transplant recipients are at an increased risk of opportunistic infections due to the use of immunosuppression. Coronavirus disease of 2019 (COVID-19) increases the risk of these infections further due to associated immune dysfunction and the use of high-dose steroids. We present a case of a liver transplant recipient who developed disseminated tuberculosis and invasive pulmonary aspergillosis complicated by acquired hemophagocytic lymphohistiocytosis after recovering from severe COVID-19.

摘要

由于使用免疫抑制药物,肝移植受者发生机会性感染的风险增加。2019冠状病毒病(COVID-19)由于相关的免疫功能障碍和大剂量类固醇的使用,进一步增加了这些感染的风险。我们报告一例肝移植受者,该患者在从重症COVID-19康复后发生播散性结核病和侵袭性肺曲霉病,并并发获得性噬血细胞性淋巴组织细胞增生症。

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