可编程四面体框架核酸基纳米材料在神经系统疾病中的应用：进展与展望
Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects.
作者信息
Chen Xingyu, Xie Yu, Liu Zhiqiang, Lin Yunfeng
机构信息
State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
College of Biomedical Engineering, Sichuan University, Chengdu, China.
出版信息
Front Bioeng Biotechnol. 2021 Nov 26;9:782237. doi: 10.3389/fbioe.2021.782237. eCollection 2021.
Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, is widely applied in diverse biomedical fields. Due to its high programmability, biocompatibility, tissue permeability as well as its capacity for cell proliferation and differentiation, tFNA presents a powerful tool that could overcome potential barriers in the treatment of neurological disorders. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.
四面体框架核酸（tFNA）是一种特殊的DNA纳米器件，广泛应用于各种生物医学领域。由于其高度的可编程性、生物相容性、组织渗透性以及促进细胞增殖和分化的能力，tFNA是一种强大的工具，能够克服神经疾病治疗中的潜在障碍。本文综述评估了基于tFNA的纳米材料在神经疾病治疗中的应用及进展的近期研究。
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