Yendo Tatiana Mina, Gabbi Tatiana Villas Boas, Nico Marcello Menta Simonsen
Department of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Skin Appendage Disord. 2021 Nov;7(6):489-492. doi: 10.1159/000516304. Epub 2021 May 25.
The lesions of porokeratosis (PK) lead to skin atrophy and scarring as long as they spread centrifugally. PK affecting the nail unit is seldom described.
The aim was to revise the previously reported cases of ungual PK and to present 3 new cases.
A PubMed search was performed with the keywords "nail" and "porokeratosis." Previously reported cases as well as 3 new cases are depicted in tables.
Only 11 cases of ungual PK were found; 3 new cases have been added. All patients presented with typical lesions of PK (Mibelli, isolated, segmental, or ostial eccrine types) that happened to affect nails due to nail matrix or nail bed compromise, resulting in mild to severe nail scarring, including irreversible anonychia. The present 3 case series contrast with the previous single case reports.
PK affecting the nails is exceedingly rare. Changes in nails affected by PK are irreversible, since, as on the skin, this is a chronic scarring process.
只要匐行性穿通性弹力纤维病（PK）呈离心性扩散，其病变就会导致皮肤萎缩和瘢痕形成。影响甲单位的PK很少被描述。
旨在复习先前报道的甲部PK病例，并报告3例新病例。
使用关键词“指甲”和“匐行性穿通性弹力纤维病”在PubMed上进行检索。先前报道的病例以及3例新病例以表格形式呈现。
仅发现11例甲部PK；新增3例。所有患者均表现为典型的PK病变（米贝利型、孤立型、节段型或汗孔型），因甲母质或甲床受损而累及指甲，导致轻至重度甲瘢痕形成，包括不可逆的无甲。本3例系列病例与先前的单病例报告有所不同。
影响指甲的PK极为罕见。受PK影响的指甲变化是不可逆的，因为这与皮肤病变一样，是一个慢性瘢痕形成过程。
