Caerulines A and B, Flavonol Diacylglycosides from .

Two undescribed 4'--methylkaempferol-[3″,4″-di--coumaroyl]-α-l-rhamnopyranosides, caerulines A and B (), along with three known 4'--methylkaempferol diacylrhamnosides isomers () were isolated from an ethanol extract of the leaves of , a native plant growing on the Colombian Caribbean coast. The chemical structures of and were elucidated by spectroscopic methods. The effect of compounds against four pathogenic microorganisms [i.e., methicillin-resistant (MRSA), , and ] was tested . The compounds exhibited no activity against these pathogens except MRSA (MIC 12-48 μg/mL). Caeruline B () was found to be the most active compound with a modest anti-MRSA activity (MIC = 12 μg/mL).