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[非霍奇金淋巴瘤:细胞表面标志物表型与临床特征及预后的相关性]

[Non-Hodgkin's lymphoma: correlation of cell surface marker phenotype with clinical features and prognosis].

作者信息

Okabe K, Toki H, Kimura Y, Fujii M, Kiura K, Moriwaki S

出版信息

Gan To Kagaku Ryoho. 1986 Oct;13(10):2960-4.

PMID:3490224
Abstract

The correlation of surface marker phenotype with prognosis was analysed in 64 patients with non-Hodgkin's lymphoma who had been treated in Shikoku Cancer Center Hospital. B-cell lymphomas (21 cases) had significantly better prognosis than T-cell lymphomas (21 cases). The complete remission (CR) rate was 52%, and the 50% survival time was 13 months for T-cell lymphomas. All T-cell lymphoma patients died within 31 months. In B-cell lymphomas, on the other hand, the CR rate was 100%, 50% survival time was 30 months, and there were no cases of relapse in patients who had been in continuous CR for more than 2 years. About 40% of B-cell lymphomas appeared to have the potential for cure.

摘要

对在四国癌症中心医院接受治疗的64例非霍奇金淋巴瘤患者的表面标志物表型与预后的相关性进行了分析。B细胞淋巴瘤(21例)的预后明显优于T细胞淋巴瘤(21例)。T细胞淋巴瘤的完全缓解(CR)率为52%,50%生存时间为13个月。所有T细胞淋巴瘤患者均在31个月内死亡。另一方面,在B细胞淋巴瘤中,CR率为100%,50%生存时间为30个月,持续CR超过2年的患者无复发病例。约40%的B细胞淋巴瘤似乎有治愈的可能。

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