Department of Gastroenterology, Jinhua Hospital of Zhejiang University, Jinhua, Zhejiang Province, China.
J Int Med Res. 2021 Dec;49(12):3000605211061042. doi: 10.1177/03000605211061042.
Coeliac disease (CD) is an autoimmune small bowel disease that occurs in susceptible individuals that develop an immunological reaction to gluten. A strict gluten-free diet (GFD) is the primary treatment for CD. This case report describes a patient with CD recurrence due to a discontinuation of a strict GFD by the patient. After recurrence, the patient developed fever and pancytopaenia, and quickly died of haemophagocytic lymphohistiocytosis (HLH). To the best of our knowledge, this is the first description of a case of CD associated with HLH due to discontinued GFD, which may contribute to improving the awareness of the importance of maintaining a strict GFD and having regular follow-up examinations.
乳糜泻（CD）是一种自身免疫性小肠疾病，发生在易患个体中，这些个体对麸质产生免疫反应。严格的无麸质饮食（GFD）是 CD 的主要治疗方法。本病例报告描述了一名患者因停止严格 GFD 而导致 CD 复发。复发后，患者出现发热和全血细胞减少，并迅速死于噬血细胞性淋巴组织细胞增生症（HLH）。据我们所知，这是首例因停止 GFD 而导致 CD 相关 HLH 的病例描述，这可能有助于提高对维持严格 GFD 和定期随访检查重要性的认识。
