Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan .
Retina. 2022 Apr 1;42(4):730-737. doi: 10.1097/IAE.0000000000003376.
To investigate the prevalence of ciliochoroidal effusion (CE) in central serous chorioretinopathy (CSC) using anterior-segment optical coherence tomography and its association with the clinical features of CSC.
Overall, 164 eyes of 164 patients with CSC and 51 eyes of 51 age- and sex-matched normal control participants were retrospectively examined. Anterior-segment optical coherence tomography was used to assess patients with CSC and control subjects for CE and scleral thickness. Central serous chorioretinopathy eyes were divided into two groups: eyes with CE (CE group) and eyes without CE (non-CE group). Scleral thickness was measured at the point that was 6 mm posterior to the scleral spur in four directions.
Among the 164 eyes with CSC, 32 eyes (19.5%) displayed CE, and this proportion was significantly higher than that in control subjects (2.0%) (P = 0.001). Scleral thickness was significantly greater in the CE group compared with the non-CE group at all four directions (P < 0.05 for all). Multivariable analysis revealed that the mean scleral thickness (odds ratio: 1.01; 95% confidence interval: 1.00-1.02; P = 0.007) was significantly associated with the incidence of CE.
Central serous chorioretinopathy may accompany fluid accumulation in the anterior segment more frequently than previously expected in association with thick sclera.
使用眼前节光学相干断层扫描（OCT）研究中心性浆液性脉络膜视网膜病变（CSC）中睫状体脉络膜渗漏（CE）的患病率，并探讨其与 CSC 临床特征的关系。
回顾性分析了 164 例（164 只眼）CSC 患者和 51 例（51 只眼）年龄和性别匹配的正常对照组患者的资料。使用眼前节 OCT 评估 CSC 患者和对照组患者的 CE 和巩膜厚度。将 CSC 眼分为两组：有 CE（CE 组）和无 CE（非 CE 组）。在四个方向上，在巩膜突后 6mm 处测量巩膜厚度。
在 164 只 CSC 眼中，32 只（19.5%）出现 CE，这一比例明显高于对照组（2.0%）（P=0.001）。CE 组的巩膜厚度在四个方向上均显著大于非 CE 组（P<0.05）。多变量分析显示，平均巩膜厚度（优势比：1.01；95%置信区间：1.00-1.02；P=0.007）与 CE 的发生显著相关。
CSC 可能比以前预期的更常伴有前节液体积聚，同时伴有巩膜增厚。
