Center for Neurointestinal Health, Massachusetts General Hospital.
Harvard Medical School.
J Pediatr Gastroenterol Nutr. 2022 May 1;74(5):588-592. doi: 10.1097/MPG.0000000000003369. Epub 2021 Dec 13.
Recent reports document avoidant/restrictive food intake disorder (ARFID) symptoms among 13-40% of adults presenting to neurogastroenterology clinics, but ARFID in pediatrics is understudied. We conducted a retrospective review of charts from 129 consecutive referrals (ages 6-18 years; 57% female) for pediatric neurogastroenterology examination, from January 2016 through December 2018. Eleven cases (8%) met the full criteria for ARFID by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition and 19 cases (15%) had clinically significant avoidant/ restrictive eating behaviors with insufficient information for a definitive ARFID diagnosis. Of patients with ARFID symptoms (n = 30), 20 (67%) cited fear of gastrointestinal symptoms as motivation for their avoidant/ restrictive eating. Compared to patients without ARFID symptoms, patients with ARFID symptoms were older (P < .001), more likely to be female (51% vs 79%, P = 0.014), and more frequently presented with eating/weight-related complaints (15% vs 33%, P = 0.026). This pilot retrospective study showed ARFID symptoms present in 23% of pediatric neurogastroenterology patients; further research is needed to understand risk and maintenance factors of ARFID in the neurogastroenterology setting.
最近的报告记录了在到神经胃肠病学诊所就诊的 13%至 40%的成年人中存在回避/限制型食物摄入障碍(ARFID)症状,但儿科的 ARFID 研究较少。我们对 2016 年 1 月至 2018 年 12 月期间的 129 例连续转诊(年龄 6-18 岁;57%为女性)进行了回顾性图表审查,这些患者均因小儿神经胃肠病学检查而转诊。11 例(8%)符合《精神障碍诊断与统计手册》第 5 版的 ARFID 全部标准,19 例(15%)存在临床显著的回避/限制进食行为,但缺乏明确 ARFID 诊断的充分信息。在有 ARFID 症状的患者(n=30)中,有 20 例(67%)表示对胃肠道症状的恐惧是他们回避/限制进食的动机。与没有 ARFID 症状的患者相比,有 ARFID 症状的患者年龄更大(P<0.001),更可能为女性(51%比 79%,P=0.014),更常出现与饮食/体重相关的抱怨(15%比 33%,P=0.026)。这项初步的回顾性研究显示,小儿神经胃肠病学患者中有 23%存在 ARFID 症状;需要进一步研究以了解神经胃肠病学环境中 ARFID 的风险和维持因素。