系统性红斑狼疮的神经精神受累：病例系列
Neuropsychiatric involvement in systemic lupus erythematosus: A case series.
作者信息
Gupta Nishtha, Arya Aakansha, Ali Tahoora, Chaudhari Bhushan
机构信息
Department of Psychiatry, Dr. D. Y. Patil Medical College, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.
出版信息
Ind Psychiatry J. 2021 Oct;30(Suppl 1):S201-S203. doi: 10.4103/0972-6748.328870. Epub 2021 Oct 22.
Abstract
Patients with systemic lupus erythematous that suffers from one or more of several neuropsychiatric symptoms represent a subcategory termed "neuropsychiatric systemic lupus erythematosus" (NPSLE). Different environmental factors, such as infection, stress, and ischemia, mediated by inflammatory cytokines, may damage the blood-brain barrier, further contributing to neuropsychiatric symptoms. Antiribosomal-P antibodies are specifically related to psychosis in NPSLE. Three patients of systemic lupus erythematosus who developed features of psychosis are presented and the condition is briefly discussed.
摘要
患有几种神经精神症状中的一种或多种的系统性红斑狼疮患者代表了一个被称为“神经精神性系统性红斑狼疮”（NPSLE）的亚类。由炎性细胞因子介导的不同环境因素，如感染、压力和局部缺血，可能会损害血脑屏障，进一步导致神经精神症状。抗核糖体P抗体与NPSLE中的精神病特别相关。本文介绍了3例出现精神病特征的系统性红斑狼疮患者，并对该病症进行了简要讨论。
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J Rheumatol. 2014 Sep;41(9):1823-33. doi: 10.3899/jrheum.140111. Epub 2014 Aug 15.
2
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Nat Rev Rheumatol. 2014 Jun;10(6):338-47. doi: 10.1038/nrrheum.2014.15. Epub 2014 Feb 11.
3
Neuropsychiatric systemic lupus erythematosus: magnetic resonance imaging findings and correlation with clinical and immunological features.神经精神性狼疮：磁共振成像表现与临床和免疫学特征的相关性。
Autoimmun Rev. 2013 Oct;12(12):1166-70. doi: 10.1016/j.autrev.2013.07.004. Epub 2013 Jul 11.
4
Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome.系统性红斑狼疮和抗磷脂综合征中的运动障碍。
J Neural Transm (Vienna). 2013 Nov;120(11):1579-89. doi: 10.1007/s00702-013-1023-z. Epub 2013 Apr 13.
5
Neuropsychiatric syndromes in systemic lupus erythematosus: a meta-analysis.神经精神性狼疮的神经精神性综合征：一项荟萃分析。
Semin Arthritis Rheum. 2011 Aug;41(1):1-11. doi: 10.1016/j.semarthrit.2010.08.001. Epub 2010 Oct 20.
6
Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus.系统性红斑狼疮女性患者中情绪和焦虑障碍的患病率
Arthritis Rheum. 2009 Jun 15;61(6):822-9. doi: 10.1002/art.24519.
7
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9
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