Ghosh M, McCulloch C
Can J Ophthalmol. 1986 Oct;21(6):246-52.
A 45-year-old lady presented with a recurrent corneal erosion. On closer examination, she was found to have epithelial microcysts and fingerprint dystrophy. Pathologic material from the affected cornea showed microcysts, protrusions of basement membrane and evidence of poor adhesion between the basement membrane and the epithelial cells, as well as between the epithelial cells themselves. The case demonstrated the clinical and pathologic features of recurrent corneal erosion, microcystic disease and fingerprint dystrophy of the cornea, together with the pathologic findings of map dystrophy. The authors suggest that these four diseases are various expressions of a clinicopathologic entity, epithelial basement membrane corneal dystrophy. A pathologic explanation for recurrent corneal erosion is apparent.
一位45岁女性因复发性角膜糜烂就诊。经仔细检查,发现她患有上皮微囊肿和指纹状营养不良。取自患眼角膜的病理材料显示有微囊肿、基底膜突出,以及基底膜与上皮细胞之间、上皮细胞自身之间黏附性差的证据。该病例展示了复发性角膜糜烂、微囊肿性疾病、角膜指纹状营养不良的临床和病理特征,以及地图状营养不良的病理表现。作者认为这四种疾病是一种临床病理实体——上皮基底膜角膜营养不良的不同表现形式。复发性角膜糜烂的病理原因显而易见。