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病毒感染的营养调节——对2019冠状病毒病的启示

Nutrient modulation of viral infection-implications for COVID-19.

作者信息

Kim Hye-Keong, Park Chan Yoon, Han Sung Nim

机构信息

Department of Food Science and Nutrition, The Catholic University of Korea, Bucheon, Korea.

Department of Food and Nutrition, College of Health Science, The University of Suwon, Hwaseong, Korea.

出版信息

Nutr Res Pract. 2021 Dec;15(Suppl 1):S1-S21. doi: 10.4162/nrp.2021.15.S1.S1. Epub 2021 Jun 28.

DOI:10.4162/nrp.2021.15.S1.S1
PMID:34909129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8636392/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic has put focus on the importance of a healthy immune system for recovery from infection and effective response to vaccination. Several nutrients have been under attention because their nutritional statuses showed associations with the incidence or severity of COVID-19 or because they affect several aspects of immune function. Nutritional status, immune function, and viral infection are closely interrelated. Undernutrition impairs immune function, which can lead to increased susceptibility to viral infection, while viral infection itself can result in changes in nutritional status. Here, we review the roles of vitamins A, C, D, and E, and zinc, iron, and selenium in immune function and viral infection and their relevance to COVID-19.

摘要

2019年冠状病毒病(COVID-19)大流行使人们关注健康免疫系统对于从感染中康复以及对疫苗接种做出有效反应的重要性。几种营养素受到关注,因为它们的营养状况与COVID-19的发病率或严重程度相关,或者因为它们影响免疫功能的多个方面。营养状况、免疫功能和病毒感染密切相关。营养不良会损害免疫功能,这可能导致对病毒感染的易感性增加,而病毒感染本身会导致营养状况的变化。在此,我们综述维生素A、C、D和E,以及锌、铁和硒在免疫功能和病毒感染中的作用及其与COVID-19的相关性。

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本文引用的文献

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Folate Levels in Patients Hospitalized with Coronavirus Disease 2019.COVID-19 住院患者的叶酸水平。
Nutrients. 2021 Mar 2;13(3):812. doi: 10.3390/nu13030812.
2
Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2.维生素 A 对感染的抵抗力和恢复:与 SARS-CoV2 的相关性。
Br J Nutr. 2021 Dec 14;126(11):1663-1672. doi: 10.1017/S0007114521000246. Epub 2021 Jan 20.
3
Evaluation of maternal serum afamin and vitamin E levels in pregnant women with COVID-19 and its association with composite adverse perinatal outcomes.评价 COVID-19 孕妇血清 afamin 和维生素 E 水平及其与复合不良围产结局的关系。
J Med Virol. 2021 Apr;93(4):2350-2358. doi: 10.1002/jmv.26725. Epub 2020 Dec 23.
4
Vitamin deficiency as risk factor for SARS-CoV-2 infection: correlation with susceptibility and prognosis.维生素缺乏作为 SARS-CoV-2 感染的风险因素:与易感性和预后的相关性。
Eur Rev Med Pharmacol Sci. 2020 Sep;24(18):9721-9738. doi: 10.26355/eurrev_202009_23064.
5
Increased Serum Levels of Hepcidin and Ferritin Are Associated with Severity of COVID-19.血清铁调素和铁蛋白水平升高与 COVID-19 严重程度相关。
Med Sci Monit. 2020 Sep 26;26:e926178. doi: 10.12659/MSM.926178.
6
Effect of Vitamin A Deficiency in Dysregulating Immune Responses to Influenza Virus and Increasing Mortality Rates After Bacterial Coinfections.维生素 A 缺乏症对流感病毒免疫反应的调节作用及其在细菌合并感染后死亡率增加的影响。
J Infect Dis. 2021 May 28;223(10):1806-1816. doi: 10.1093/infdis/jiaa597.
7
SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels.与循环 25-羟维生素 D 水平相关的 SARS-CoV-2 阳性率。
PLoS One. 2020 Sep 17;15(9):e0239252. doi: 10.1371/journal.pone.0239252. eCollection 2020.
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Int J Infect Dis. 2020 Nov;100:343-349. doi: 10.1016/j.ijid.2020.09.014. Epub 2020 Sep 10.
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Iron chelation may harm patients with COVID-19.铁螯合疗法可能对新冠肺炎患者造成伤害。
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Could Vitamins Help in the Fight Against COVID-19?维生素能帮助对抗新冠病毒吗?
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