Lauriola L, Tallini G, Sentinelli S, Massi G
Cell Tissue Res. 1986;246(1):77-80. doi: 10.1007/BF00219002.
The presence of different serum proteins in the cells of the proximal tubule of both meso- and metanephric nephrons in human embryos (7th-12th week of intrauterine life) was investigated using immunohistochemistry. Endogenous lysozyme, alpha-1-antitrypsin and ferritin were detected in mesonephric proximal tubules and, starting from the 8th week, also in metanephric proximal tubules. Our observations provide information concerning the appearance and distribution of tubular protein reabsorption during the early stages of development.
利用免疫组织化学方法，对人类胚胎（子宫内生活7至12周）中肾和后肾肾单位近端小管细胞中不同血清蛋白的存在情况进行了研究。在内源性溶菌酶、α-1抗胰蛋白酶和铁蛋白在中肾近端小管中被检测到，并且从第8周开始，在后肾近端小管中也被检测到。我们的观察结果提供了有关发育早期肾小管蛋白重吸收的出现和分布的信息。
