Fujimoto Tomotaka, Yanishi Kenji, Zen Kan, Matoba Satoaki
Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kajii-cho 465, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Eur Heart J Case Rep. 2021 Nov 30;5(12):ytab484. doi: 10.1093/ehjcr/ytab484. eCollection 2021 Dec.
Spontaneous coronary artery rupture (SCAR) is an extremely rare and highly lethal disease.
A 74-year-old man who had undergone respiratory surgery (robot-assisted thoracoscopic surgery) presented with exertional dyspnoea since postoperative day (POD) 6. Echocardiography and contrast-enhanced computed tomography showed diffuse pericardial effusion, and a 12-lead electrocardiogram showed widespread concave ST-segment elevation. The diagnosis of acute pericarditis was made based on the absence of significant elevation of cardiac enzymes and the presence of elevated C-reactive peptide levels. The patient was started on anti-inflammatory medication, including steroids; however, on POD 11, the patient developed a sudden cardiopulmonary arrest due to cardiac tamponade. Extracorporeal cardiopulmonary resuscitation was performed, and an emergency coronary angiography showed contrast extravasation from the left anterior descending artery to the epicardium. He was diagnosed with SCAR and underwent transcatheter arterial embolization (TAE) and pericardial drainage.
In this case, SCAR occurred during the course of acute pericarditis. We speculated that the cause of SCAR was more affected with pericarditis than injury by the respiratory surgery. The clinical course of acute pericarditis generally has a good prognosis, but the rare occurrence of fatal complications should be considered, suggesting the need for careful follow-up. In addition, TAE was a less invasive and feasible treatment for SCAR.
自发性冠状动脉破裂(SCAR)是一种极其罕见且致死率很高的疾病。
一名74岁男性,接受了呼吸外科手术(机器人辅助胸腔镜手术),自术后第6天起出现劳力性呼吸困难。超声心动图和增强计算机断层扫描显示弥漫性心包积液,12导联心电图显示广泛的凹面ST段抬高。根据心肌酶无显著升高且C反应蛋白水平升高,诊断为急性心包炎。患者开始使用包括类固醇在内的抗炎药物治疗;然而,在术后第11天,患者因心脏压塞突然发生心肺骤停。进行了体外心肺复苏,急诊冠状动脉造影显示造影剂从左前降支动脉外渗至心外膜。他被诊断为SCAR,并接受了经导管动脉栓塞术(TAE)和心包引流。
在本病例中,SCAR发生在急性心包炎病程中。我们推测SCAR的病因受心包炎的影响大于呼吸手术造成的损伤。急性心包炎的临床病程通常预后良好,但应考虑罕见的致命并发症的发生,这表明需要仔细随访。此外,TAE是一种治疗SCAR的侵入性较小且可行的方法。