Samanci Nilay Sengul, Akdogan Selma, Celik Emir, Kutlu Ozce, Ulgen Ovgu Aydin, Demirelli Fuat Hulusi
Department of Medical Oncology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
Department of Internal Medicine, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
North Clin Istanb. 2020 Jul 23;8(5):518-520. doi: 10.14744/nci.2020.23500. eCollection 2021.
Skin metastasis caused by carcinomas is associated with poor prognosis and is a rare and late clinical finding. Skin metastases occur in only 4-6.5% of Stage IV colorectal cancer. We present an unusual case of Stage IV unresectable rectal adenocarcinoma metastasized to the head and face. One and a half years after diagnosis, new skin lesions developed on his face. Biopsy showed mucinous adenocarcinoma consistent with rectal malignancy. Moreover, he died 3 months after the diagnosis of cutaneous metastasis. This case emphasizes the importance of the effect of skin lesions on prognosis in patients with a history of malignancy.
癌引起的皮肤转移与预后不良相关，是一种罕见的晚期临床发现。皮肤转移仅发生在4% - 6.5%的IV期结直肠癌患者中。我们报告一例不寻常的IV期不可切除直肠腺癌转移至头面部的病例。诊断后一年半，患者面部出现新的皮肤病变。活检显示为黏液腺癌，与直肠恶性肿瘤相符。此外，在诊断皮肤转移后3个月，他去世了。该病例强调了皮肤病变对有恶性肿瘤病史患者预后影响的重要性。
