Coll-Mazzei J, Devolfe C, Jegaden O, Marquarti V, Boukili A, Adeleine P, Corsini B, Mikaeloff P
Arch Mal Coeur Vaiss. 1985 Sep;78(9):1306-11.
The results of saphenous vein coronary bypass alone were assessed in 126 patients operated between 1970 and 1972 with a postoperative follow-up period of 10 to 12 years. Spontaneous or unstable angina was observed in 72% and incapacitating effort angina in 27.7%. An average of 1.8 grafts per patient was carried out but revascularisation remained incomplete in 51.6% of cases. The early postoperative mortality was 1.58%; the early postoperative infarct rate was 12.7%. There were 47 late deaths, most of which were of cardiac origin (53.2%) or due to cerebrovascular accidents (12.8%). Actuarial survival studies showed an annual mortality rate of 3.2%. The overall 10 to 12 year survival rate was 68.4. The secondary infarction rate was 13.7%, an annual rate of less than 1.5%. Control coronary angiography was carried out in 112 patients; 78% of the grafts remained patent at 2 years. Age (p less than 0.008), basal ECG changes (p less than 0.003) and left ventricular function (p less than 0.05) were significant prognostic factors for survival. One year after surgery, 63.5% of patients were angina free. Thereafter, the annual recurrence rate for angina was 3.1%. After 10 years, 35.4% of patients remained free of angina. A statistical analysis of the factors influencing the recurrence of angina showed that the number of coronary stenoses (p less than 0.02) and the quality of revascularisation (p less than 0.001) were significant factors. After an average follow-up of 75.7 months, 9 patients were reoperated using the internal mammary to revascularize the left anterior descending artery. Sixty per cent of the operated patients were able to return to work.
对1970年至1972年间接受手术的126例患者单独进行了隐静脉冠状动脉搭桥术的结果评估,术后随访期为10至12年。观察到72%的患者出现自发性或不稳定型心绞痛,27.7%的患者出现致残性劳力性心绞痛。每位患者平均进行了1.8次移植,但51.6%的病例血运重建仍不完全。术后早期死亡率为1.58%;术后早期梗死率为12.7%。有47例晚期死亡,其中大多数死于心脏原因(53.2%)或脑血管意外(12.8%)。精算生存研究显示年死亡率为3.2%。10至12年的总生存率为68.4%。二次梗死率为13.7%,年发生率低于1.5%。对112例患者进行了对照冠状动脉造影;2年后78%的移植血管保持通畅。年龄(p<0.008)、基础心电图改变(p<0.003)和左心室功能(p<0.05)是生存的重要预后因素。术后1年,63.5%的患者无心绞痛。此后,心绞痛的年复发率为3.1%。10年后,35.4%的患者仍无心绞痛。对影响心绞痛复发因素的统计分析表明,冠状动脉狭窄数量(p<0.02)和血运重建质量(p<0.001)是重要因素。平均随访75.7个月后,9例患者再次手术,使用乳内动脉对左前降支进行血运重建。60%的手术患者能够重返工作岗位。