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一名成年男性中偶然发现的川崎病。

Incidentally discovered Kawasaki disease in an adult man.

作者信息

Haider Kamel H, Alshoabi Sultan Abdulwadoud, Qurashi Abdulaziz A, Hamid Abdullgabbar M

机构信息

Kamel H. Haider, Cardiology Department, Prince Mohammed Bin Nasser Hospital, Jazan, Kingdom of Saudi Arabia.

Sultan Abdulwadoud Alshoabi, Department of Diagnostic Radiology Technology, College of Applied Medical Sciences, Taibah University, Almadinah Almunawwarah, Kingdom of Saudi Arabia.

出版信息

Pak J Med Sci. 2021 Nov-Dec;37(7):2032-2034. doi: 10.12669/pjms.37.7.4199.

DOI:10.12669/pjms.37.7.4199
PMID:34912440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8613055/
Abstract

Kawasaki disease (KD) is a systemic vasculitis of unknown cause which usually diagnosed in small children. However, KD can be present as coronary disease in adults even with no history of the disease in childhood. Here, we describe a case of KD in a 42-year-old male patient presented with severe retrosternal chest pain radiating to the left arm and provisionally diagnosed as acute coronary disease. Coronary artery ectasia and multiple aneurysms have been confirmed by coronary angiography that led to the diagnosis of KD. The patient was treated with Aspirin 81 mg orally once daily, Apixapan 5 mg orally twice daily, Rosuvastatin 40 mg orally once daily, Bisoprolol 5 mg orally once daily, and omeprazole 20 mg orally once daily. The patient was improved and discharged with anticoagulant drugs for life. Physicians should be aware that KD can be present as coronary disease in adults even with no history of the disease in childhood and has a limited treatment options due to unfavorable coronary anatomy.

摘要

川崎病(KD)是一种病因不明的全身性血管炎,通常在幼儿中被诊断出来。然而,KD即使在儿童期没有该病病史,也可能在成人中表现为冠状动脉疾病。在此,我们描述一例42岁男性患者的KD病例,该患者表现为严重的胸骨后胸痛并向左臂放射,初步诊断为急性冠状动脉疾病。冠状动脉造影证实了冠状动脉扩张和多发动脉瘤,从而确诊为KD。该患者接受了如下治疗:阿司匹林81毫克,每日口服一次;阿哌沙班5毫克,每日口服两次;瑞舒伐他汀40毫克,每日口服一次;比索洛尔5毫克,每日口服一次;奥美拉唑20毫克,每日口服一次。患者病情好转并出院,需终身服用抗凝药物。医生应意识到,KD即使在儿童期没有该病病史,也可能在成人中表现为冠状动脉疾病,并且由于冠状动脉解剖结构不佳,治疗选择有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/cb4ecb040056/PJMS-37-2032-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/7a85cd22c68e/PJMS-37-2032-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/86278960261f/PJMS-37-2032-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/cb4ecb040056/PJMS-37-2032-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/7a85cd22c68e/PJMS-37-2032-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/86278960261f/PJMS-37-2032-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27af/8613055/cb4ecb040056/PJMS-37-2032-g003.jpg

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本文引用的文献

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Insights Into Coronary Artery Lesions in Kawasaki Disease.川崎病冠状动脉病变的研究进展
Front Pediatr. 2020 Aug 25;8:493. doi: 10.3389/fped.2020.00493. eCollection 2020.
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A History of Kawasaki Disease From Childhood and Coronary Artery Ectasia With Recurrent ST Elevation Myocardial Infarction: A Therapeutic Challenge.一名患有川崎病并伴有冠状动脉扩张及复发性ST段抬高型心肌梗死儿童的病史:一项治疗挑战。
Cardiol Res. 2017 Dec;8(6):344-348. doi: 10.14740/cr641w. Epub 2017 Dec 22.
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Long-term consequences of Kawasaki disease. A 10- to 21-year follow-up study of 594 patients.川崎病的长期后果。对594例患者进行的10至21年随访研究。
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