He Ying, Ji Hao, Xie Jian-Chang, Zhou Liang
The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China.
Department of Cardiology, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.
World J Clin Cases. 2022 Oct 6;10(28):10266-10272. doi: 10.12998/wjcc.v10.i28.10266.
Kawasaki disease (KD) is a self-limiting febrile illness and an acute vasculitis with an unknown origin. It predominantly affects children aged < 5 years. KD is the common cause of acquired heart disease in children. We here report a case of KD in an asymptomatic young female patient diagnosed with multiple coronary aneurysms with calcification.
A 29-year-old female patient admitted to Hangzhou First People's Hospital with coronary artery abnormality identified for 1 wk. The patient was asymptomatic; however, chest computed tomography occasionally revealed strip-like dense shadows in the coronal sulcus. After coronary angiography and Doppler echocardiography, the final diagnosis was coronary artery aneurysms (CAAs) caused by KD. Although the patient was asymptomatic with no history of KD in childhood, the definitive diagnosis was CAAs caused by KD. The patient was administered anticoagulant, and surgical treatment was recommended.
KD potentially causes CAAs in 25% of untreated cases, primarily occurring in the proximal portions of the coronary arteries.
川崎病（KD）是一种自限性发热性疾病，是一种病因不明的急性血管炎。它主要影响5岁以下儿童。KD是儿童后天性心脏病的常见病因。我们在此报告一例无症状年轻女性川崎病患者，诊断为多发冠状动脉瘤伴钙化。
一名29岁女性患者因冠状动脉异常1周入住杭州市第一人民医院。患者无症状；然而，胸部计算机断层扫描偶尔显示冠状沟有条状致密阴影。经冠状动脉造影和多普勒超声心动图检查后，最终诊断为川崎病所致冠状动脉瘤（CAA）。尽管患者无症状且儿童时期无川崎病病史，但确诊为川崎病所致CAA。给予患者抗凝治疗，并建议手术治疗。
在25%未经治疗的病例中，川崎病可能导致CAA，主要发生在冠状动脉近端。
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