Doi Takahito, Kawarada Osami, Matsuyama Taka-Aki, Ayabe Shinobu, Ishibashi-Ueda Hatsue, Noguchi Teruo, Ogawa Hisao, Yasuda Satoshi
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Department of Cardiovascular Medicine, Ikuwakai Memorial Hospital, Osaka, Japan.
AsiaIntervention. 2019 Feb;5(1):53-56. doi: 10.4244/AIJ-D-18-00057. Epub 2019 Feb 20.
Calcified lesions pose a technical challenge even in contemporary endovascular intervention. A 71-year-old man who had been receiving haemodialysis required infrapopliteal revascularisation for the treatment of ischaemic infectious gangrene of the right toes. Baseline angiography suggested that the multiple stenotic lesions in the anterior tibial artery were amenable to endovascular therapy for the purpose of establishing one straight-line flow to the foot. However, even a 1.25×15 mm semi-compliant balloon catheter failed to cross and dilate the focal lesion because of the underlying severe calcification in the mid segment of the anterior tibial artery. We adjunctively used high-speed rotational atherectomy with the ROTABLATOR device (1.5 mm burr) to ablate the focal calcified lesion while paying attention to minimise the ablation length and the ablation time. Subsequent balloon angioplasty with a 2.0×40 mm balloon catheter was successful. The skin perfusion pressure in the right foot increased from 32 to 48 mmHg, suggesting a high probability of wound healing. Pathological examination of the right toe amputated on schedule found non-clinically relevant microembolisation involving a couple of cholesterol crystals (20-30 µm) located in the arterioles and capillaries of the necrotic tissue. As an adjunctive device, the ROTABLATOR could provide a last resort for limb salvage, albeit that microembolisation can occur.
钙化病变即使在当代血管内介入治疗中也构成技术挑战。一名71岁接受血液透析的男性因右脚趾缺血性感染性坏疽需要进行腘下血管重建术。基线血管造影显示,胫前动脉的多处狭窄病变适合进行血管内治疗,以建立一条通向足部的直线血流。然而,由于胫前动脉中段存在严重钙化,即使使用1.25×15毫米的半顺应性球囊导管也无法穿过并扩张局部病变。我们辅助使用ROTABLATOR装置(1.5毫米磨头)进行高速旋磨术,以消融局部钙化病变,同时注意尽量缩短消融长度和时间。随后使用2.0×40毫米球囊导管进行球囊血管成形术获得成功。右脚的皮肤灌注压从32毫米汞柱升至48毫米汞柱,提示伤口愈合的可能性很大。按计划对右脚趾进行截肢后的病理检查发现,坏死组织的小动脉和毛细血管中有少量胆固醇结晶(20 - 30微米),存在与临床无关的微栓塞现象。作为一种辅助装置,ROTABLATOR尽管可能会发生微栓塞,但可为肢体挽救提供最后的手段。