Suppr超能文献

机器人辅助部分肾切除术对 99m-Tc DTPA 肾闪烁显像评估的长期肾功能的影响。

Influence of Robot-Assisted Partial Nephrectomy on Long-Term Renal Function as Assessed Using 99m-Tc DTPA Renal Scintigraphy.

机构信息

Department of Urology, Iwate Medical University, Shiwa-gun, Japan.

出版信息

J Endourol. 2022 May;36(5):641-646. doi: 10.1089/end.2021.0243.

Abstract

The long-term split renal function after robot-assisted partial nephrectomy (RAPN) is yet to be elucidated. This study aimed to assess long-term renal function of RAPN, using renal scintigraphy, and to identify clinical factors related to deterioration of renal function on the affected side of the kidney. RAPN for small tumors was performed, and split renal function was evaluated using 99m-Tc DTPA renal scintigraphy before and 1 year after surgery. Clinical factors (age, gender, body mass index, tumor side, presence of urinary protein, diabetes, hypertension, and dyslipidemia), perioperative factors (renal nephrectomy score [RNS], tumor diameter, overall surgery duration, console time, warm ischemic time, and amount of bleeding), and renal function (estimated glomerular filtration rate [eGFR] and glomerular filtration rate [GFR] measured using scintigraphy on both the affected and contralateral kidneys) were analyzed. Sixty-six patients were included in the study. The median eGFR decreased from 71.9 to 63.9 mL/min after 1 year ( < 0.001), accounting for a mean loss of 10.1%. In scintigraphy examination, the median GFR on the affected kidney side decreased from 41.1 to 33.7 mL/min after 1 year ( < 0.001), accounting for a mean loss of 16.8%. RNS was significantly associated with renal function. Among RNS factors, the N factor is associated with renal function after RAPN. RNS, particularly the N factor, possibly influences the long-term deterioration of renal function after RAPN.

摘要

机器人辅助部分肾切除术(RAPN)后长期分肾功能尚不清楚。本研究旨在使用肾闪烁显像术评估 RAPN 的长期肾功能,并确定与肾功能恶化相关的临床因素。对小肿瘤进行 RAPN,术前和术后 1 年使用 99m-Tc DTPA 肾闪烁显像术评估分肾功能。分析临床因素(年龄、性别、体重指数、肿瘤侧、尿蛋白、糖尿病、高血压和血脂异常)、围手术期因素(肾切除术评分[RNS]、肿瘤直径、总手术时间、控制台时间、热缺血时间和出血量)以及肾功能(受影响和对侧肾脏闪烁显像测量的估算肾小球滤过率[eGFR]和肾小球滤过率[GFR])。研究纳入 66 例患者。1 年后,eGFR 中位数从 71.9 降至 63.9 mL/min( < 0.001),平均损失 10.1%。在闪烁显像检查中,受影响侧肾脏的 GFR 中位数从 41.1 降至 33.7 mL/min( < 0.001),平均损失 16.8%。RNS 与肾功能显著相关。在 RNS 因素中,N 因素与 RAPN 后的肾功能相关。RNS,特别是 N 因素,可能会影响 RAPN 后肾功能的长期恶化。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验