Queen Adele E, Selmani Aymane, Schoenebeck Franziska
Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Org Lett. 2022 Jan 14;24(1):406-409. doi: 10.1021/acs.orglett.1c04088. Epub 2021 Dec 16.
This Letter discloses the straightforward hydrogermylation of olefins under visible-light organophotoredox-initiated HAT catalysis conditions to yield primary and secondary alkyl germanes at room temperature. The protocol is operationally simple, metal-free, and tolerant of various functional groups. The synthesized alkyl germanes proved to be highly robust toward acidic, basic, or oxidizing conditions and chemical transformations of C-GeEt or C-BPin functionalities in their presence.
这封信披露了在可见光有机光氧化还原引发的氢原子转移（HAT）催化条件下烯烃的直接氢锗化反应，可在室温下生成伯烷基锗和仲烷基锗。该方法操作简单、无金属且耐受各种官能团。合成的烷基锗在酸性、碱性或氧化条件下以及在其存在下C-GeEt或C-BPin官能团的化学转化中表现出高度稳定性。
