Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi 110029, India.
Department of Microbiology, All India Institute of Medical Sciences, New Delhi 110029, India.
Sex Health. 2022 Jan;18(6):512-514. doi: 10.1071/SH21149.
Bacterial vaginosis (BV) is diagnosed by the microbiological Nugent scoring method or clinical Amsel's criteria. Assessment of 404 vaginal samples (293 women) identified 110 (27.2%), 108 (26.7%) and 161 (39.9%) samples to be BV-positive using Nugent's method, standard Amsel's criteria and simplified Amsel's criteria respectively. The sensitivity, specificity, and kappa statistic (κ) for standard and simplified Amsel's criteria were 71.8% (95% CI=62.4-80.0), 90.1% (95% CI=62.4-86.1), 0.62 (95% CI=0.53-0.72) and 88.2% (95% CI=80.6-93.6), 78.2% (95% CI=73.1-82.8), 0.58 (95% CI=0.49-0.67), respectively. A combination of vaginal pH and clue cells exhibited the highest concordance (κ=0.64, 95% CI=0.54-0.74) with Nugent's method and may be used for simplified BV diagnosis.
细菌性阴道病 (BV) 通过微生物学 Nugent 评分法或临床 Amsel 标准进行诊断。对 404 个阴道样本（293 名女性）进行评估，使用 Nugent 法、标准 Amsel 标准和简化 Amsel 标准分别将 110 个（27.2%）、108 个（26.7%）和 161 个（39.9%）样本诊断为 BV 阳性。标准和简化 Amsel 标准的敏感性、特异性和 Kappa 统计量（κ）分别为 71.8%（95%CI=62.4-80.0）、90.1%（95%CI=62.4-86.1）、0.62（95%CI=0.53-0.72）和 88.2%（95%CI=80.6-93.6）、78.2%（95%CI=73.1-82.8）、0.58（95%CI=0.49-0.67）。阴道 pH 值和线索细胞的组合与 Nugent 法具有最高的一致性（κ=0.64，95%CI=0.54-0.74），可用于简化 BV 诊断。
