Mohammadzadeh Farnaz, Dolatian Mahrokh, Jorjani Masoome, Alavi Majd Hamid
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Glob J Health Sci. 2014 Oct 29;7(3):8-14. doi: 10.5539/gjhs.v7n3p8.
Bacterial vaginosis (BV) is one of the most prevalent infections in women of reproductive age. Amsel's criteria and Nugent scoring system are among the most commonly used diagnostic methods. Although Nugent scoring system is considered the gold standard for diagnosing BV, it is time consuming and costly, and its interpretation needs lab equipment and experts. Hence, most physicians are inclined to use simpler clinical criteria that are yet accurate instead.The present study aimed to determine the diagnostic value of Amsel's criteria in diagnosing BV.
MATERIALS & METHODS: This present study was conducted to validate diagnostic tests of BVin 120 married women in 2013. Amsel's criteria and Nugent scoring system were used to diagnose BV. Nugent scoring system was considered the gold standard and sensitivity, specificity, positive predictive value and negative predictive value of Amsel's criteria were compared with those of Nugent scoring system.
Kappa coefficient was used to assess the diagnostic value of Nugent scoring system and Amsel's criteria. Kappa coefficient was found 0.8, which confirms the reliability of both diagnostic methods. McNemar test did not reveal a significant difference between Nugent scoring system and Amsel's criteria in terms of diagnosing BV. As compared to Nugent scoring system, Asmel's criteria enjoy sensitivity of 0.91, specificity of 0.91, positive predictive value of 0.86, negative predictive value of 0.94, and accuracy of 0.91.
If lab equipment is not available for diagnosing BV, Amsel's criteria can be as good as Nugent scoring system at diagnosing this infection.
细菌性阴道病(BV)是育龄女性中最常见的感染之一。阿姆塞尔标准和纽金特评分系统是最常用的诊断方法。尽管纽金特评分系统被认为是诊断BV的金标准,但它耗时且成本高,其解读需要实验室设备和专家。因此,大多数医生倾向于使用更简单但仍准确的临床标准。本研究旨在确定阿姆塞尔标准在诊断BV中的诊断价值。
本研究于2013年对120名已婚女性进行,以验证BV的诊断测试。采用阿姆塞尔标准和纽金特评分系统诊断BV。将纽金特评分系统视为金标准,并将阿姆塞尔标准的敏感性、特异性、阳性预测值和阴性预测值与纽金特评分系统进行比较。
使用kappa系数评估纽金特评分系统和阿姆塞尔标准的诊断价值。kappa系数为0.8,证实了两种诊断方法的可靠性。麦克尼马尔检验未显示纽金特评分系统和阿姆塞尔标准在诊断BV方面存在显著差异。与纽金特评分系统相比,阿姆塞尔标准的敏感性为0.91,特异性为0.91,阳性预测值为0.86,阴性预测值为0.94,准确性为0.91。
如果没有实验室设备用于诊断BV,阿姆塞尔标准在诊断这种感染方面与纽金特评分系统一样好。