Nugmanova Zh S, Nugmanova D S, Sukhodoeva G S, Beklemishev N D
Zh Mikrobiol Epidemiol Immunobiol. 1986 Sep(9):48-53.
The distribution of T- and B-lymphocytes in the body of guinea pigs was studied in different groups of the animals. As shown in this study, in delayed hypersensitivity to staphylococci the number of PE- and E-rosette-forming cells increased in the blood, the spleen, and the lymph nodes and decreased in the thymus; the number of EA- and EAC-rosette-forming cells decreased in the bone marrow and the spleen, the number of T gamma-suppressors decreased in the bone marrow and the distant lymph node. Immediate hypersensitivity to tarragon pollen induced the general increase of the content of T- and B-lymphocytes; the number of T gamma-cells decreased in the thymus, the bone marrow, and the lymph nodes and increased in the spleen. The characteristic features of combined microbial-pollen sensitization were the high content of B-cells in all lymphoid organs (except the thymus), a low level of T-lymphocytes in the blood and the peripheral lymphoid organs, the decreased number of T gamma-cells in most of the immunogenetic organs.
在豚鼠的不同组中研究了T淋巴细胞和B淋巴细胞在其体内的分布。如本研究所示，在对葡萄球菌的迟发型超敏反应中，血液、脾脏和淋巴结中形成PE花环和E花环的细胞数量增加，而胸腺中则减少；骨髓和脾脏中形成EA花环和EAC花环的细胞数量减少，骨髓和远处淋巴结中Tγ抑制细胞数量减少。对龙蒿花粉的速发型超敏反应导致T淋巴细胞和B淋巴细胞含量普遍增加；胸腺、骨髓和淋巴结中Tγ细胞数量减少，而脾脏中则增加。微生物-花粉联合致敏的特征是所有淋巴器官（胸腺除外）中B细胞含量高，血液和外周淋巴器官中T淋巴细胞水平低，大多数免疫遗传器官中Tγ细胞数量减少。
