Clinical Medical College, Yangzhou University, Yangzhou, China.
Dongtai People's Hospital, Dongtai, China.
Urol Int. 2022;106(9):909-913. doi: 10.1159/000520373. Epub 2021 Dec 15.
The aim of this study was to evaluate the clinical value of 16 G biopsy needle in transperineal template-guided prostate biopsy (TTPB), compared with 18 G biopsy needle.
The patients who underwent TTPB from August 2020 to February 2021 were randomized into 2 groups using a random number table. The control group (n = 65) and the observation group (n = 58) performed biopsy with 18 G (Bard MC l820) and 16 G (Bard MC l616) biopsy needles, respectively. Positive rate of biopsy, Gleason score, complications, and pain score were statistically analyzed.
The age, prostate volume, PSA, and the number of cores were comparable between the 2 groups. The positive rate of biopsy in the observation group was 68.9% (40/58), meanwhile the control group was 46.2% (30/65). There was statistical difference between the 2 groups (p = 0.011). Gleason score of the observation group (8 [7-9]) was higher than that of the control group (8 [6-9]) (p = 0.038). There was no significant difference in pain score and complications including hematuria, hematospermia, perineal hematoma, infection, and urinary retention between the 2 groups (p > 0.05).
16 G biopsy needle significantly improved the positive rates and accurately evaluate the nature of lesions, meanwhile did not increase the incidence of complications compared with 18 G biopsy needle.
本研究旨在评估 16G 活检针在经会阴模板引导前列腺活检（TTPB）中的临床价值，并与 18G 活检针进行比较。
采用随机数字表法将 2020 年 8 月至 2021 年 2 月接受 TTPB 的患者随机分为两组。对照组（n=65）和观察组（n=58）分别使用 18G（Bard MC l820）和 16G（Bard MC l616）活检针进行活检。统计分析活检阳性率、Gleason 评分、并发症和疼痛评分。
两组患者的年龄、前列腺体积、PSA 和活检针数无统计学差异。观察组活检阳性率为 68.9%（40/58），对照组为 46.2%（30/65），两组比较差异有统计学意义（p=0.011）。观察组的 Gleason 评分（8[7-9]）高于对照组（8[6-9]）（p=0.038）。两组疼痛评分和血尿、血精、会阴血肿、感染、尿潴留等并发症发生率无统计学差异（p>0.05）。
与 18G 活检针相比，16G 活检针可显著提高活检阳性率，准确评估病变性质，且不增加并发症发生率。
