Department of Pediatrics, University of Washington, 4800 Sand Point Way NE, M/S MB.7.520, Seattle, WA98105, USA.
Seattle Children's Hospital, Seattle, USA.
Public Health Nutr. 2023 Jan;26(1):246-255. doi: 10.1017/S1368980021004894. Epub 2021 Dec 17.
To assess the effectiveness of outpatient management with ready-to-use and supplementary foods for infants under 6 months (u6m) of age who were unable to be treated as inpatients due to social and economic barriers.
Review of operational acute malnutrition treatment records.
Twenty-one outpatient therapeutic feeding clinics in rural Malawi.
Infants u6m with acute malnutrition treated as outpatients because of barriers to inpatient treatment. The comparison group consisted of acutely malnourished children 6-9 months of age who were being treated at the same time in the same location in the context of two different randomised clinical trials.
A total of 323 infants u6m were treated for acute malnutrition (130 severe and 193 moderate). A total of 357 infants 6-9 months old with acute malnutrition (seventy-four severe and 283 moderate) were included as contemporaneous controls. Among infants u6m with severe acute malnutrition, 98 (75·4 %) achieved nutritional recovery; in comparison, 56 (75·7 %) of those with severe acute malnutrition 6-9 months old recovered. Among infants u6m with moderate acute malnutrition, 157 (81·3 %) recovered; in comparison, 241 (85·2 %) of those aged 6-9 months recovered.
In a rural Malawian population of infants u6m who had generally already stopped exclusive breast-feeding and were now acutely malnourished, treatment with therapeutic or supplementary foods under the community management of acute malnutrition model was safe and effective. In settings where social and financial factors make hospital admission challenging, consideration should be given to lowering the recommended age of ready-to-use therapeutic and supplementary foods to infants u6m.
评估针对因社会经济障碍而无法住院治疗的 6 月龄以下婴儿(u6m)的门诊管理中使用即食和补充食品的效果。
回顾操作性急性营养不良治疗记录。
马拉维 21 个农村门诊治疗喂养诊所。
u6m 患有急性营养不良的婴儿,因住院治疗的障碍而作为门诊接受治疗。对照组由同时在同一地点、同一位置接受治疗的 6-9 个月大、患有急性营养不良的儿童组成,这是两项不同的随机临床试验的一部分。
共治疗了 323 例 u6m 急性营养不良婴儿(130 例严重和 193 例中度)。同时还纳入了 357 例 6-9 个月大、患有急性营养不良的婴儿(74 例严重和 283 例中度)作为同期对照。在患有严重急性营养不良的 u6m 婴儿中,98 例(75.4%)实现了营养恢复;相比之下,6-9 个月大的严重急性营养不良婴儿中有 56 例(75.7%)恢复。在患有中度急性营养不良的 u6m 婴儿中,157 例(81.3%)恢复;相比之下,6-9 个月大的婴儿中有 241 例(85.2%)恢复。
在马拉维农村地区,一般已经停止纯母乳喂养且患有急性营养不良的 u6m 婴儿中,采用社区管理急性营养不良模式用治疗性或补充食品进行治疗是安全有效的。在社会和经济因素使住院治疗具有挑战性的环境中,应考虑将即食治疗性和补充食品的推荐年龄降低至 6 月龄以下。